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a-methapred

Pharmaranks rates A-Methapred 2.9/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. A-Methapred (Methylprednisolone Sodium Succinate) is a corticosteroid used to treat Adrenal Insufficiency, Asthma, Berylliosis, Brain Neoplasms.

Methylprednisolone Sodium Succinate · by Hospira

Generic of Solu-Medrol

⚠ FDA reports a current shortage of the injection form — availability differs between suppliers — see drug shortages →
58/100Limited · 1 source

Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →

Rated against independent regulatory sources·Last updated October 8, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Drug class
Corticosteroid
Form
Injectable
Strength
Methylprednisolone Sodium Succinate EQ 125MG BASE/VIAL
Type
Prescription (Rx)
Brand or generic
Generic
Manufacturer
Hospira
What the pharmacy pays
~$30.69 for 30 — not your price
FDA application
ANDA040827
Availability
Discontinued (per FDA)

Drug class

How this class works, per Corticosteroids - StatPearls - NCBI Bookshelf.

May treat (source: NIH RxClass)

Dosage forms

Injectable

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does A-Methapred treat?
A-Methapred (Methylprednisolone Sodium Succinate) may be used to treat adrenal insufficiency, asthma, berylliosis, brain neoplasms, ulcerative colitis, dermatitis herpetiformis, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does A-Methapred work?
A-Methapred is a corticosteroid. Corticosteroids mimic the body's natural stress hormone cortisol: they enter cells and bind a glucocorticoid receptor that switches off genes for inflammatory chemicals, calming swelling, redness, and an overactive immune response.
How is A-Methapred rated?
pharmaranks gives A-Methapred a composite score of 2.9 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
How much does A-Methapred cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $30.69 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for A-Methapred?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell A-Methapred. To pay less, A-Methapred is already a generic — usually the lowest-cost version — so the main levers are comparing cash prices between pharmacies and using a pharmacy discount-card service. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes A-Methapred?
A-Methapred is marketed by Hospira. You can see Hospira's full profile, rating, and other products on pharmaranks.
Is A-Methapred a brand-name or generic drug?
A-Methapred is a generic medication; its active ingredient is Methylprednisolone Sodium Succinate. Generics contain the same active ingredient as the brand-name original and are usually lower cost.
Is A-Methapred available over the counter?
No. A-Methapred is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does A-Methapred come in?
A-Methapred is currently marketed as injectable, per the FDA's National Drug Code Directory.
What class of drug is A-Methapred?
A-Methapred is classified as corticosteroid, per the FDA's Established Pharmacologic Class.
Is A-Methapred FDA-registered?
A-Methapred is on record with the U.S. FDA under application number ANDA040827. You can verify this on its official FDA label.
Has A-Methapred been recalled by the FDA?
A-Methapred has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
Is A-Methapred safe?
There's no single safe-or-not verdict. pharmaranks gives A-Methapred a recall-safety score of 58/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

What people report to the FDA about METHYLPREDNISOLONE SODIUM SUCCINATE

The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 18,519 reports naming METHYLPREDNISOLONE SODIUM SUCCINATE — the active ingredient in A-Methapred, and the FDA flagged 97% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:

  • fatigue2,348 reports
  • infusion related reaction2,336 reports
  • headache2,321 reports
  • nausea2,084 reports
  • rash1,880 reports
  • pyrexia1,869 reports
  • rheumatoid arthritis1,863 reports
  • hypertension1,777 reports

Read these as a signal, not a rate. A report does not mean METHYLPREDNISOLONE SODIUM SUCCINATE caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.

Source: openFDA drug/event (FAERS), retrieved September 25, 2026.

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a-methapred

58/100