OXYCODONE AND ACETAMINOPHEN vs ROXICET 5/500

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 11, 2026·How we rate

Attribute	OXYCODONE AND ACETAMINOPHEN	ROXICET 5/500
Rating	72/100	70/100
Pharmacy pays	$0.03 /mL	$0.03 /mL
Type	RX	RX
Active ingredient	ACETAMINOPHEN AND OXYCODONE HYDROCHLORIDE	ACETAMINOPHEN AND OXYCODONE HYDROCHLORIDE
Manufacturer	Mallinckrodt	Roxane
Dosage forms	Solution, Tablet	Tablet
Drug class	—	—
Boxed warning	None	None
Half-life	about 3.5 to 4 hours	about 3.5 to 4 hours

oxycodone and acetaminophen roxicet 5/500

Rating

72/100

70/100

Pharmacy pays

$0.03 /mL

Type

Active ingredient

ACETAMINOPHEN AND OXYCODONE HYDROCHLORIDE

Manufacturer

Mallinckrodt

Roxane

Dosage forms

Solution, Tablet

Tablet

Drug class

—

Boxed warning

None

Half-life

about 3.5 to 4 hours

Frequently asked questions

Which is better-rated, Oxycodone and Acetaminophen or Roxicet 5/500?

By our independent rating, Oxycodone and Acetaminophen scores higher — 3.6 vs 3.5 out of 5 for Roxicet 5/500. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Oxycodone and Acetaminophen or Roxicet 5/500?

Pharmacies pay about the same to acquire either one — roughly $0.03 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Oxycodone and Acetaminophen and Roxicet 5/500?

Both Oxycodone and Acetaminophen and Roxicet 5/500 share the active ingredient Acetaminophen and Oxycodone Hydrochloride.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.