Skip to content
ppharmaranks
Menu

oxycodone and acetaminophen

Pharmaranks rates Oxycodone and Acetaminophen 3.5/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Oxycodone and Acetaminophen is a combination medicine containing Acetaminophen and Oxycodone Hydrochloride.

Acetaminophen and Oxycodone Hydrochloride · by Mallinckrodt

Generic of Xartemis XR

70/100Limited · 1 source

Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Acetaminophen and Oxycodone Hydrochloride
Form
Solution, Tablet
Strength
Acetaminophen 500MG; Oxycodone Hydrochloride 7.5MG · Acetaminophen 650MG; Oxycodone Hydrochloride 10MG
Type
Prescription (Rx)
Brand or generic
Generic
Manufacturer
Mallinckrodt
Half-life
about 3.5 to 4 hours (how long it stays in your system)
What the pharmacy pays
~$0.03 per ml — not your price
FDA application
ANDA040550
Availability
Discontinued (per FDA)

How long does Acetaminophen and Oxycodone Hydrochloride stay in your body?

The elimination half-life of acetaminophen and oxycodone hydrochloride is about 3.5 to 4 hours — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the elimination half-life for immediate-release oxycodone in adults with normal organ function; extended/controlled-release products act longer, and in kidney or liver impairment oxycodone concentrations run higher and clearance is reduced. The main metabolites (noroxycodone, oxymorphone) are not longer-acting than the parent drug for immediate-release oxycodone.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: OXYCODONE HYDROCHLORIDE tablet — DailyMed.

Dosage forms

Solution and Tablet

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

How is Oxycodone and Acetaminophen rated?
pharmaranks gives Oxycodone and Acetaminophen a composite score of 3.5 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
How much does Oxycodone and Acetaminophen cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.03 per ml, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for Oxycodone and Acetaminophen?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Oxycodone and Acetaminophen. To pay less, Oxycodone and Acetaminophen is already a generic — usually the lowest-cost version — so the main levers are comparing cash prices between pharmacies and using a pharmacy discount-card service. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Oxycodone and Acetaminophen?
Oxycodone and Acetaminophen is marketed by Mallinckrodt. You can see Mallinckrodt's full profile, rating, and other products on pharmaranks.
Is Oxycodone and Acetaminophen a brand-name or generic drug?
Oxycodone and Acetaminophen is a generic medication; its active ingredient is Acetaminophen and Oxycodone Hydrochloride. Generics contain the same active ingredient as the brand-name original and are usually lower cost.
Is Oxycodone and Acetaminophen available over the counter?
No. Oxycodone and Acetaminophen is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Oxycodone and Acetaminophen come in?
Oxycodone and Acetaminophen is currently marketed as solution and tablet, per the FDA's National Drug Code Directory.
Is Oxycodone and Acetaminophen FDA-registered?
Oxycodone and Acetaminophen is on record with the U.S. FDA under application number ANDA040550. You can verify this on its official FDA label.
Has Oxycodone and Acetaminophen been recalled by the FDA?
Oxycodone and Acetaminophen has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
Is Oxycodone and Acetaminophen safe?
There's no single safe-or-not verdict. pharmaranks gives Oxycodone and Acetaminophen a recall-safety score of 70/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

Reviews

No reviews yet. Be the first to write one.

Write a review

Reviews are user opinions, not medical advice. Consult a licensed professional.

People also viewed

Compare Oxycodone and Acetaminophen head-to-head

Guides for this medication

Identify a pill by its imprint →Check a drug interaction →Drug recalls →

Browse medications A–Z

Research products from A to Z, compare independent ratings, and find alternatives.

oxycodone and acetaminophen

70/100