DESYREL vs TRAZODONE HYDROCHLORIDE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Attribute	DESYREL	TRAZODONE HYDROCHLORIDE
Rating	New	New
Pharmacy pays	~$1.52 /30	~$1.52 /30
Type	RX	RX
Active ingredient	TRAZODONE HYDROCHLORIDE	TRAZODONE HYDROCHLORIDE
Manufacturer	Pragma	Crossmedika Sa
Dosage forms	Tablet	Tablet
Drug class	Serotonin Reuptake Inhibitor	Serotonin Reuptake Inhibitor
Boxed warning	None	None
Half-life	about 7 hours (roughly 5 to 9 hours for the slower elimination phase)	about 7 hours (roughly 5 to 9 hours for the slower elimination phase)
Treats	Depressive Disorder, Sleep Initiation and Maintenance Disorders	Depressive Disorder, Sleep Initiation and Maintenance Disorders

desyrel trazodone hydrochloride

Rating

New

Pharmacy pays

~$1.52 /30

Type

Active ingredient

TRAZODONE HYDROCHLORIDE

Manufacturer

Pragma

Crossmedika Sa

Dosage forms

Tablet

Drug class

Serotonin Reuptake Inhibitor

Boxed warning

None

Half-life

about 7 hours (roughly 5 to 9 hours for the slower elimination phase)

Treats

Depressive Disorder, Sleep Initiation and Maintenance Disorders

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Frequently asked questions

Which is cheaper, Desyrel or Trazodone Hydrochloride?

Pharmacies pay about the same to acquire either one — roughly $1.52 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Desyrel and Trazodone Hydrochloride?

Both Desyrel and Trazodone Hydrochloride share the active ingredient Trazodone Hydrochloride.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.