Best Phosphodiesterase 5 Inhibitor for hypertension, pulmonary
Top-rated pick: Vybrique — pharmaranks score 72/100, the highest of the 7 Phosphodiesterase 5 Inhibitor drugs used for hypertension, pulmonary, ranked by our independent FDA recall-safety score. Compare them with all treatments for hypertension, pulmonary or the full Phosphodiesterase 5 Inhibitor class. Not medical advice — always consult a professional.
Quick answer: Of the 7 phosphodiesterase 5 inhibitor drugs we rate for hypertension, pulmonary, all are available as lower-cost generics, and most are tablet. Our ranking reflects each drug’s FDA recall-safety record — not clinical effectiveness for hypertension, pulmonary; the right choice depends on your situation, so confirm it with your prescriber.
How phosphodiesterase 5 inhibitor work
PDE5 inhibitors block the enzyme that breaks down cGMP, a signal that relaxes blood vessels. Letting cGMP build up widens vessels and boosts blood flow, which helps erectile dysfunction and eases pressure in the lung arteries.
Other drug classes for hypertension, pulmonary
Top phosphodiesterase 5 inhibitor for hypertension, pulmonary: 1. Vybrique · 2. Adcirca · 3. Revatio
| # | Drug | Rating | Type | Form | Generic? | Pharmacy pays | |
|---|---|---|---|---|---|---|---|
| 1 | 72/100 | Prescription | Film | Generic | $0 | View → | |
| 2 | 70/100 | Prescription | Tablet | Generic | $4 | View → | |
| 3 | 70/100 | Prescription | Injectable | Generic | $0 | View → | |
| 4 | 70/100 | Prescription | Tablet | Generic | $0 | View → | |
| 5 | 56/100 | Prescription | Tablet | Generic | $4 | View → | |
| 6 | Not yet rated | Prescription | Tablet | Generic | $4 | View → | |
| 7 | Not yet rated | Prescription | Suspension | Generic | $4 | View → |
Full ranking · 7 drugs
vybrique
PrescriptionFDA-sourced
Vybrique (Sildenafil Citrate) is a phosphodiesterase 5 inhibitor used to treat Pulmonary Hypertension, Vasculogenic Impotence.
Pharmacy pays
From ~$0.05· 5 formsadcirca
PrescriptionFDA-sourced
Adcirca (Tadalafil) is a phosphodiesterase 5 inhibitor used to treat Pulmonary Hypertension, Vasculogenic Impotence.
Pharmacy pays
From ~$3.13/30· 4 forms
revatio
PrescriptionFDA-sourced
Revatio (Sildenafil Citrate) is a phosphodiesterase 5 inhibitor used to treat Pulmonary Hypertension, Vasculogenic Impotence.
Pharmacy pays
From ~$0.05· 5 formsviagra
PrescriptionFDA-sourced
Viagra (Sildenafil Citrate) is a phosphodiesterase 5 inhibitor used to treat Pulmonary Hypertension, Vasculogenic Impotence.
Pharmacy pays
From ~$0.05· 5 formsalyq
PrescriptionFDA-sourced
Alyq (Tadalafil) is a phosphodiesterase 5 inhibitor used to treat Pulmonary Hypertension, Vasculogenic Impotence.
Pharmacy pays
From ~$3.13/30· 4 formscialis
PrescriptionFDA-sourced
Cialis (Tadalafil) is a phosphodiesterase 5 inhibitor used to treat Pulmonary Hypertension, Vasculogenic Impotence.
Pharmacy pays
From ~$3.13/30· 4 formstadliq
PrescriptionFDA-sourced
Tadliq (Tadalafil) is a phosphodiesterase 5 inhibitor used to treat Pulmonary Hypertension, Vasculogenic Impotence.
Pharmacy pays
From ~$3.13/30· 4 formsFrequently asked
- What is the best phosphodiesterase 5 inhibitor for hypertension, pulmonary?
- By our independent recall-safety rating — not an efficacy measure — vybrique ranks highest among Phosphodiesterase 5 Inhibitor drugs used for hypertension, pulmonary. Always consult a professional.
- Which phosphodiesterase 5 inhibitor drugs treat hypertension, pulmonary?
- pharmaranks lists 7 Phosphodiesterase 5 Inhibitor products used for hypertension, pulmonary, per NIH RxClass drug-classification data — each independently rated and ranked above.
- How are these ranked?
- By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.