Best Phenothiazine for schizophrenia
Top-rated pick: Procomp — pharmaranks score 70/100, the highest of the 4 Phenothiazine drugs used for schizophrenia, ranked by our independent FDA recall-safety score. Compare them with all treatments for schizophrenia or the full Phenothiazine class. Not medical advice — always consult a professional.
Quick answer: Of the 4 phenothiazine drugs we rate for schizophrenia, 3 are available as lower-cost generics, and most are tablet. Our ranking reflects each drug’s FDA recall-safety record — not clinical effectiveness for schizophrenia; the right choice depends on your situation, so confirm it with your prescriber.
Other drug classes for schizophrenia
Top phenothiazine for schizophrenia: 1. Procomp · 2. Perphenazine · 3. Prochlorperazine Edisylate
| # | Drug | Rating | Type | Form | Generic? | Pharmacy pays | |
|---|---|---|---|---|---|---|---|
| 1 | 70/100 | Prescription | Tablet | Generic | $5 | View → | |
| 2 | 68/100 | Prescription | Tablet | Generic | $6 | View → | |
| 3 | Not yet rated | Prescription | Injectable | No data | — | View → | |
| 4 | Not yet rated | Prescription | Tablet | Generic | $5 | View → |
Full ranking · 4 drugs
procomp
PrescriptionFDA-sourced
Procomp (Prochlorperazine Maleate) is a phenothiazine used to treat Anxiety Disorders, Dementia, Nausea, Psychotic Disorders.
Pharmacy pays
From ~$3.48/30· 3 forms Save up to 71% in class
perphenazine
Boxed warningPrescriptionFDA-sourced
Perphenazine is a phenothiazine used to treat Tourette Syndrome, Huntington Disease, Nausea, Psychotic Disorders.
Pharmacy pays
From ~$4.95/30· 4 forms Save up to 73% in classprochlorperazine edisylate
Boxed warningPrescriptionFDA-sourced
Prochlorperazine Edisylate is a phenothiazine used to treat Anxiety Disorders, Dementia, Nausea, Psychotic Disorders.
prochlorperazine maleate
Boxed warningPrescriptionFDA-sourced
Prochlorperazine Maleate is a phenothiazine used to treat Anxiety Disorders, Dementia, Nausea, Psychotic Disorders.
Pharmacy pays
From ~$3.48/30· 3 forms Save up to 71% in classFrequently asked
- What is the best phenothiazine for schizophrenia?
- By our independent recall-safety rating — not an efficacy measure — procomp ranks highest among Phenothiazine drugs used for schizophrenia. Always consult a professional.
- Which phenothiazine drugs treat schizophrenia?
- pharmaranks lists 4 Phenothiazine products used for schizophrenia, per NIH RxClass drug-classification data — each independently rated and ranked above.
- How are these ranked?
- By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.