Best Carbonic Anhydrase Inhibitor for glaucoma, open-angle
Top-rated pick: Dorzolamide Hydrochloride — pharmaranks score 70/100, the highest of the 2 Carbonic Anhydrase Inhibitor drugs used for glaucoma, open-angle, ranked by our independent FDA recall-safety score. Compare them with all treatments for glaucoma, open-angle or the full Carbonic Anhydrase Inhibitor class. Not medical advice — always consult a professional.
Quick answer: Of the 2 carbonic anhydrase inhibitor drugs we rate for glaucoma, open-angle, all are available as lower-cost generics, and most are solution. Our ranking reflects each drug’s FDA recall-safety record — not clinical effectiveness for glaucoma, open-angle; the right choice depends on your situation, so confirm it with your prescriber.
How carbonic anhydrase inhibitor work
These block the enzyme carbonic anhydrase, which normally helps the body recycle bicarbonate. In the kidneys this flushes more bicarbonate, sodium, and water into the urine, and in the eye it cuts production of the fluid that builds up pressure, which is why they treat conditions like glaucoma and altitude sickness.
Source: Carbonic Anhydrase Inhibitors - StatPearls - NCBI Bookshelf
Other drug classes for glaucoma, open-angle
Top carbonic anhydrase inhibitor for glaucoma, open-angle: 1. Dorzolamide Hydrochloride · 2. Azopt
| # | Drug | Rating | Type | Form | Generic? | Pharmacy pays | |
|---|---|---|---|---|---|---|---|
| 1 | 70/100 | Prescription | Solution | Generic | $1 | View → | |
| 2 | 68/100 | Prescription | Drops | Generic | $10 | View → |
Full ranking · 2 drugs
dorzolamide hydrochloride
PrescriptionFDA-sourced
Dorzolamide Hydrochloride is a carbonic anhydrase inhibitor used to treat Open-Angle Glaucoma.
Pharmacy pays
$0.87 /mL
azopt
PrescriptionFDA-sourced
Azopt (Brinzolamide) is a carbonic anhydrase inhibitor used to treat Open-Angle Glaucoma.
Pharmacy pays
$10.28 /mL
Save up to 92% in classFrequently asked
- What is the best carbonic anhydrase inhibitor for glaucoma, open-angle?
- By our independent recall-safety rating — not an efficacy measure — dorzolamide hydrochloride ranks highest among Carbonic Anhydrase Inhibitor drugs used for glaucoma, open-angle. Always consult a professional.
- Which carbonic anhydrase inhibitor drugs treat glaucoma, open-angle?
- pharmaranks lists 2 Carbonic Anhydrase Inhibitor products used for glaucoma, open-angle, per NIH RxClass drug-classification data — each independently rated and ranked above.
- How are these ranked?
- By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.