Best Anti-epileptic Agent for epilepsies, partial
Top-rated pick: Lamictal — pharmaranks score 70/100, the highest of the 16 Anti-epileptic Agent drugs used for epilepsies, partial, ranked by our independent FDA recall-safety score. Compare them with all treatments for epilepsies, partial or the full Anti-epileptic Agent class. Not medical advice — always consult a professional.
Quick answer: Of the 16 anti-epileptic agent drugs we rate for epilepsies, partial, all are available as lower-cost generics, and most are tablet. Our ranking reflects each drug’s FDA recall-safety record — not clinical effectiveness for epilepsies, partial; the right choice depends on your situation, so confirm it with your prescriber.
How anti-epileptic agent work
Anti-epileptic (anticonvulsant) drugs calm the abnormal, excessive electrical activity that triggers seizures. They do this by stabilizing overactive sodium or calcium channels in nerve cells, boosting the brain's natural calming chemical GABA, or dampening excitatory signals, which makes nerves less likely to fire uncontrollably.
Source: Seizure Medications — StatPearls, NCBI Bookshelf (NIH)
Other drug classes for epilepsies, partial
Top anti-epileptic agent for epilepsies, partial: 1. Lamictal · 2. Lamictal Cd · 3. Lamictal ODT
| # | Drug | Rating | Type | Form | Generic? | Pharmacy pays | |
|---|---|---|---|---|---|---|---|
| 1 | 70/100 | Prescription | Tablet | Generic | $4 | View → | |
| 2 | 70/100 | Prescription | Tablet | Generic | $4 | View → | |
| 3 | 70/100 | Prescription | Tablet | Generic | $4 | View → | |
| 4 | 70/100 | Prescription | Tablet | Generic | $3 | View → | |
| 5 | 70/100 | Prescription | Tablet | Generic | $3 | View → | |
| 6 | 70/100 | Prescription | Suspension | Generic | $5 | View → | |
| 7 | 70/100 | Prescription | Suspension | Generic | $3 | View → | |
| 8 | Not yet rated | Prescription | Capsule | Generic | $1 | View → | |
| 9 | Not yet rated | Prescription | Tablet | Generic | $64 | View → | |
| 10 | Not yet rated | Prescription | Tablet | Generic | $1 | View → |
Full ranking · 16 drugs
lamictal
Boxed warningPrescriptionFDA-sourced
Lamictal (Lamotrigine) is an anti-epileptic agent used to treat Bipolar Disorder, Partial Epilepsies, Seizures, Lennox Gastaut Syndrome.
Pharmacy pays
From ~$0.88/30· 8 forms Save up to 77% in classlamictal cd
Boxed warningPrescriptionFDA-sourced
Lamictal Cd (Lamotrigine) is an anti-epileptic agent used to treat Bipolar Disorder, Partial Epilepsies, Seizures, Lennox Gastaut Syndrome.
Pharmacy pays
From ~$0.88/30· 8 forms Save up to 77% in classlamictal odt
Boxed warningPrescriptionFDA-sourced
Lamictal ODT (Lamotrigine) is an anti-epileptic agent used to treat Bipolar Disorder, Partial Epilepsies, Seizures, Lennox Gastaut Syndrome.
Pharmacy pays
From ~$0.88/30· 8 forms Save up to 77% in classmysoline
PrescriptionFDA-sourced
Mysoline (Primidone) is an anti-epileptic agent used to treat Partial Epilepsies, Tonic-Clonic Epilepsy, Tremor.
Pharmacy pays
From ~$2.84/30· 3 forms Save up to 65% in classprimidone
PrescriptionFDA-sourced
Primidone is an anti-epileptic agent used to treat Partial Epilepsies, Tonic-Clonic Epilepsy, Tremor.
Pharmacy pays
From ~$2.84/30· 3 forms Save up to 65% in class
trileptal
PrescriptionFDA-sourced
Trileptal (Oxcarbazepine) is an anti-epileptic agent used to treat Partial Epilepsies.
Pharmacy pays
From ~$3.18/30· 7 forms Save up to 80% in classzonisade
PrescriptionFDA-sourced
Zonisade (Zonisamide) is an anti-epileptic agent used to treat Partial Epilepsies.
Pharmacy pays
From ~$1.83/30· 3 forms Save up to 68% in classgabapentin
PrescriptionFDA-sourced
Gabapentin is an anti-epileptic agent used to treat Bipolar Disorder, Partial Epilepsies, Phobic Disorders, Postherpetic Neuralgia.
Pharmacy pays
From ~$0.63/30· 8 forms Save up to 16% in classgabitril
PrescriptionFDA-sourced
Gabitril (Tiagabine Hydrochloride) is an anti-epileptic agent used to treat Bipolar Disorder, Partial Epilepsies.
Pharmacy pays
From ~$58.73/30· 4 forms Save up to 98% in class
gralise
PrescriptionFDA-sourced
Gralise (Gabapentin) is an anti-epileptic agent used to treat Bipolar Disorder, Partial Epilepsies, Phobic Disorders, Postherpetic Neuralgia.
Pharmacy pays
From ~$0.63/30· 8 forms Save up to 16% in classlamictal xr
PrescriptionFDA-sourced
Lamictal XR (Lamotrigine) is an anti-epileptic agent used to treat Bipolar Disorder, Partial Epilepsies, Seizures, Lennox Gastaut Syndrome.
Pharmacy pays
From ~$0.88/30· 8 forms Save up to 77% in classlamotrigine
PrescriptionFDA-sourced
Lamotrigine is an anti-epileptic agent used to treat Bipolar Disorder, Partial Epilepsies, Seizures, Lennox Gastaut Syndrome.
Pharmacy pays
From ~$0.88/30· 8 forms Save up to 77% in classneurontin
PrescriptionFDA-sourced
Neurontin (Gabapentin) is an anti-epileptic agent used to treat Bipolar Disorder, Partial Epilepsies, Phobic Disorders, Postherpetic Neuralgia.
Pharmacy pays
From ~$0.63/30· 8 forms Save up to 16% in classoxtellar xr
PrescriptionFDA-sourced
Oxtellar XR (Oxcarbazepine) is an anti-epileptic agent used to treat Partial Epilepsies.
Pharmacy pays
From ~$3.18/30· 7 forms Save up to 80% in classsubvenite
Boxed warningPrescriptionFDA-sourced
Subvenite (Lamotrigine) is an anti-epileptic agent used to treat Bipolar Disorder, Partial Epilepsies, Seizures, Lennox Gastaut Syndrome.
Pharmacy pays
From ~$0.88/30· 8 forms Save up to 77% in classzonegran
PrescriptionFDA-sourced
Zonegran (Zonisamide) is an anti-epileptic agent used to treat Partial Epilepsies.
Pharmacy pays
From ~$1.83/30· 3 forms Save up to 68% in classFrequently asked
- What is the best anti-epileptic agent for epilepsies, partial?
- By our independent recall-safety rating — not an efficacy measure — lamictal ranks highest among Anti-epileptic Agent drugs used for epilepsies, partial. Always consult a professional.
- Which anti-epileptic agent drugs treat epilepsies, partial?
- pharmaranks lists 16 Anti-epileptic Agent products used for epilepsies, partial, per NIH RxClass drug-classification data — each independently rated and ranked above.
- How are these ranked?
- By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.