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zomig-zmt

Pharmaranks rates Zomig-Zmt 3.5/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Zomig-Zmt (Zolmitriptan) is a serotonin-1b and serotonin-1d receptor agonist used to treat Migraine Disorders.

Zolmitriptan · by Astrazeneca

Available as a generic: Zolmitriptan

70/100Limited · 1 source

Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass
~$67.24 /30
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Key facts

Active ingredient
Zolmitriptan
Form
Tablet, orally disintegrating
Strength
Zolmitriptan 2.5MG **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons** · Zolmitriptan 5MG **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons**
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Astrazeneca
Half-life
about 3 hours (how long it stays in your system)
What the pharmacy pays
~$67.24 for 30 — not your price
FDA application
NDA021231
Availability
Discontinued (per FDA)

How long does Zolmitriptan stay in your body?

The elimination half-life of zolmitriptan is about 3 hours — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. Zolmitriptan has an ACTIVE metabolite, N-desmethyl-zolmitriptan, that is 2 to 6 times more potent at the 5-HT1B/1D receptor than the parent and reaches plasma levels about two-thirds those of zolmitriptan, so it contributes a substantial part of the effect. Its elimination half-life is also approximately 3 hours per the label (it does not outlast the parent). Special populations: pharmacokinetics in healthy elderly (65-76 yr) were similar to younger adults. Renal impairment - after oral dosing, renal clearance fell about 25% in severe impairment (CrCl 5-25 mL/min), with no significant change in moderate impairment (nasal-spray data not evaluated). Hepatic impairment - in SEVERE hepatic impairment, oral zolmitriptan AUC rose about 3-fold and Cmax about 1.5-fold with Tmax roughly doubling, so exposure (and effectively half-life) is markedly increased; dose reduction is advised. This is not a drug-test detection window and not dosing guidance.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: Zolmitriptan nasal spray - DailyMed FDA label (Clinical Pharmacology 12.3).

Drug class

How this class works, per Triptans - StatPearls - NCBI Bookshelf.

May treat (source: NIH RxClass)

See how Zomig-Zmt ranks — best-rated serotonin-1b and serotonin-1d receptor agonist for:

Dosage forms

Tablet, orally disintegrating

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

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Frequently asked questions

What does Zomig-Zmt treat?
Zomig-Zmt (Zolmitriptan) may be used to treat migraine disorders, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Zomig-Zmt work?
Zomig-Zmt is a serotonin-1b and serotonin-1d receptor agonist. These migraine drugs (triptans) switch on serotonin 5-HT1B/1D receptors: they tighten the dilated blood vessels around the brain and quiet the trigeminal nerve pathway, blocking the release of pain-signaling molecules that drive a migraine attack.
How is Zomig-Zmt rated?
pharmaranks gives Zomig-Zmt a composite score of 3.5 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
How much does Zomig-Zmt cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $67.24 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for Zomig-Zmt?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Zomig-Zmt. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Zomig-Zmt?
Zomig-Zmt is marketed by Astrazeneca. You can see Astrazeneca's full profile, rating, and other products on pharmaranks.
Is Zomig-Zmt a brand-name or generic drug?
Zomig-Zmt is a brand-name product with the active ingredient Zolmitriptan. Lower-cost generic equivalents containing Zolmitriptan are available — ask your pharmacist.
Is Zomig-Zmt available over the counter?
No. Zomig-Zmt is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Zomig-Zmt come in?
Zomig-Zmt is currently marketed as tablet, orally disintegrating, per the FDA's National Drug Code Directory.
What class of drug is Zomig-Zmt?
Zomig-Zmt is classified as serotonin-1b and serotonin-1d receptor agonist, per the FDA's Established Pharmacologic Class.
Is Zomig-Zmt FDA-registered?
Zomig-Zmt is on record with the U.S. FDA under application number NDA021231. You can verify this on its official FDA label.
Has Zomig-Zmt been recalled by the FDA?
Zomig-Zmt has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
Is Zomig-Zmt safe?
There's no single safe-or-not verdict. pharmaranks gives Zomig-Zmt a recall-safety score of 70/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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