xtrelus

How long does Guaifenesin and Hydrocodone Bitartrate stay in your body?

The elimination half-life of guaifenesin and hydrocodone bitartrate is about 3.8 hours (3.8 ± 0.3 hours) — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. Hydrocodone is converted by the liver (via CYP2D6) to an active metabolite, hydromorphone; this metabolic step is well established even though this particular label's pharmacokinetics section does not name hydromorphone. The 3.8-hour value comes from a small study (five adult male subjects); clearance and half-life can be prolonged in people with impaired liver or kidney function, in older adults, and can vary with CYP2D6 metabolizer status.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: DailyMed — Hydrocodone Bitartrate and Acetaminophen (tablet), Clinical Pharmacology / Pharmacokinetics.

Frequently asked questions

How much does Xtrelus cost?

Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.07 per ml, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.

Is there a coupon or discount for Xtrelus?

pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Xtrelus. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.

Who makes Xtrelus?

Xtrelus is marketed by Eci Pharms LLC. You can see Eci Pharms LLC's full profile, rating, and other products on pharmaranks.

Is Xtrelus a brand-name or generic drug?

Xtrelus is a brand-name product with the active ingredient Guaifenesin and Hydrocodone Bitartrate.

Is Xtrelus available over the counter?

No. Xtrelus is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.

What forms does Xtrelus come in?

Xtrelus is currently marketed as tablet, per the FDA's National Drug Code Directory.

Is Xtrelus FDA-registered?

Xtrelus is on record with the U.S. FDA under application number NDA208085. You can verify this on its official FDA label.