tobrex

What is Tobrex?

From the FDA label:Tobramycin ophthalmic solution, USP 0.3% is a sterile topical ophthalmic antibiotic formulation prepared specifically for topical therapy of external ophthalmic infections. Each mL of tobramycin ophthalmic solution, USP 0.3% contains: Active: tobramycin 0.3% (3 mg). Preservative: benzalkonium chloride 0.01% (0.1 mg). Inactives: boric acid, sodium sulfate, sodium chloride, tyloxapol, sodium hydroxide and/or sulfuric acid (to adjust pH) and purified water. Tobramycin ophthalmic solution, USP 0.3% has a pH range between 7.0 and 8.0 and an osmolality of 260-320 mOsm/kg. Tobramycin is a water-soluble aminoglycoside antibiotic active against a wide variety of gram-negative and gram-positive ophthalmic pathogens. The chemical structure of tobramycin is: MW=467.52 Molecular Formula: C 18 H 37 N 5 O 9 Chemical Name: 0-{3-amino-3-deoxy-α-D-gluco-pyranosyl-(1→4)} -0- {2,6-diamino-2,3,6-trideoxy-α-D-ribohexopyranosyl-(1→6) }-2-deoxystreptamine. chemical

How to use

Side effects

Warnings

Who should not take Tobrex

Frequently asked questions

What does Tobrex treat?

Tobrex (Tobramycin) may be used to treat infectious bone diseases, central nervous system infections, pseudomonas infections, respiratory tract infections, infectious skin diseases, staphylococcal infections, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.

How does Tobrex work?

Tobrex is a aminoglycoside antibacterial. Aminoglycosides kill bacteria by latching onto the germ's protein-making machinery (the 30S ribosomal subunit). This jams and misreads the bacterial genetic code so the microbe builds faulty proteins it can't survive on, which is why these drugs destroy the bacteria rather than just stopping their growth.

How is Tobrex rated?

pharmaranks gives Tobrex a composite score of 3.4 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.

How much does Tobrex cost?

Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $1.08 per ml, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.

Is there a coupon or discount for Tobrex?

pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Tobrex. To pay less, Tobrex is already a generic — usually the lowest-cost version — so the main levers are comparing cash prices between pharmacies and using a pharmacy discount-card service. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.

Who makes Tobrex?

Tobrex is marketed by Sandoz. You can see Sandoz's full profile, rating, and other products on pharmaranks.

Is Tobrex a brand-name or generic drug?

Tobrex is a generic medication; its active ingredient is Tobramycin. Generics contain the same active ingredient as the brand-name original and are usually lower cost.

Is Tobrex available over the counter?

No. Tobrex is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.

What forms does Tobrex come in?

Tobrex is currently marketed as topical, per the FDA's National Drug Code Directory.

What class of drug is Tobrex?

Tobrex is classified as aminoglycoside antibacterial, per the FDA's Established Pharmacologic Class.

Is Tobrex FDA-registered?

Tobrex is on record with the U.S. FDA under application number ANDA062535. You can verify this on its official FDA label.

Has Tobrex been recalled by the FDA?

Tobrex has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.

Is Tobrex safe?

There's no single safe-or-not verdict. pharmaranks gives Tobrex a recall-safety score of 68/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

What are the side effects of Tobrex?

Tobrex's side effects are taken directly from its FDA label. From the label: The most frequent adverse reactions to tobramycin ophthalmic solution, 0.3% are hypersensitivity and localized ocular toxicity, including lid itching and swelling, and conjunctival erythema. These reactions occur in less than three of 100 patients treated with tobramycin ophthalmic solution, 0.3%.… Both common and serious reactions are documented in full on this page. This is general reference from the FDA, not medical advice — always consult a professional.