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sumavel dosepro

Sumavel Dosepro (Sumatriptan Succinate) is a serotonin-1b and serotonin-1d receptor agonist used to treat Cluster Headache, Migraine Disorders.

Sumatriptan Succinate · by Endo Operations

Available as a generic: Sumatriptan Succinate

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass
Lower-cost optionsSave up to 86%
This medication~$481.89/30
Cheapest in class · zomig~$67.24/30
See FDA-approved alternatives

Key facts

Active ingredient
Sumatriptan Succinate
Form
Injectable
Strength
Sumatriptan Succinate EQ 4MG BASE/0.5ML (EQ 8MG BASE/ML) · Sumatriptan Succinate EQ 6MG BASE/0.5ML (EQ 12MG BASE/ML)
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Endo Operations
Half-life
about 2 hours (terminal elimination half-life 115 ± 19 minutes) (how long it stays in your system)
What the pharmacy pays
~$481.89 for 30 — not your price
FDA application
NDA022239
Availability
Discontinued (per FDA)

How long does Sumatriptan Succinate stay in your body?

The elimination half-life of sumatriptan succinate is about 2 hours (terminal elimination half-life 115 ± 19 minutes) — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the terminal (beta) half-life; the label separately reports a much shorter distribution (alpha) half-life of 15 ± 2 minutes — the ~2-hour figure is the elimination one. Value is for the 6-mg subcutaneous injection. No active metabolite to worry about: the major metabolite, indole acetic acid (IAA) and its glucuronide, is explicitly inactive, so the parent's half-life is the whole story. Populations the label names: in older adults (mean age 72) pharmacokinetics were similar to younger healthy subjects, so no half-life change stated. Mild-to-moderate hepatic impairment showed no significant PK difference; severe hepatic impairment was not studied and this injection is contraindicated in it. The label does not report kidney-impairment data for the injection. Drug interaction: an MAO-A inhibitor raised sumatriptan AUC ~2-fold and the elimination half-life by about 40%.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: Sumatriptan Injection — DailyMed FDA Label, Section 12.3 Pharmacokinetics.

Drug class

How this class works, per Triptans - StatPearls - NCBI Bookshelf.

May treat (source: NIH RxClass)

See how Sumavel Dosepro ranks — best-rated serotonin-1b and serotonin-1d receptor agonist for:

Dosage forms

Injectable

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

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Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

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Frequently asked questions

What does Sumavel Dosepro treat?
Sumavel Dosepro (Sumatriptan Succinate) may be used to treat cluster headache, migraine disorders, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Sumavel Dosepro work?
Sumavel Dosepro is a serotonin-1b and serotonin-1d receptor agonist. These migraine drugs (triptans) switch on serotonin 5-HT1B/1D receptors: they tighten the dilated blood vessels around the brain and quiet the trigeminal nerve pathway, blocking the release of pain-signaling molecules that drive a migraine attack.
How much does Sumavel Dosepro cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $481.89 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins. Pharmacies pay less for a same-class option, Zomig — about $67.24 on the same basis.
Is there a coupon or discount for Sumavel Dosepro?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Sumavel Dosepro. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Sumavel Dosepro?
Sumavel Dosepro is marketed by Endo Operations. You can see Endo Operations's full profile, rating, and other products on pharmaranks.
Is Sumavel Dosepro a brand-name or generic drug?
Sumavel Dosepro is a brand-name product with the active ingredient Sumatriptan Succinate. Lower-cost generic equivalents containing Sumatriptan Succinate are available — ask your pharmacist.
Is Sumavel Dosepro available over the counter?
No. Sumavel Dosepro is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Sumavel Dosepro come in?
Sumavel Dosepro is currently marketed as injectable, per the FDA's National Drug Code Directory.
What class of drug is Sumavel Dosepro?
Sumavel Dosepro is classified as serotonin-1b and serotonin-1d receptor agonist, per the FDA's Established Pharmacologic Class.
Is Sumavel Dosepro FDA-registered?
Sumavel Dosepro is on record with the U.S. FDA under application number NDA022239. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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