
rizatriptan benzoate
Pharmaranks rates Rizatriptan Benzoate 3.3/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Rizatriptan Benzoate is a serotonin-1b and serotonin-1d receptor agonist used to treat Migraine Disorders.
Serotonin-1b and Serotonin-1d Receptor Agonist · by Apotex
Generic of Maxalt
Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →
Key facts
- Active ingredient
- Rizatriptan Benzoate
- Form
- Tablet, Tablet, orally disintegrating
- Strength
- Rizatriptan Benzoate EQ 10MG Base · Rizatriptan Benzoate EQ 5MG Base
- Type
- Prescription (Rx)
- Brand or generic
- Generic
- May treat
- migraine disorders
- Manufacturer
- Apotex
- Half-life
- about 2 to 3 hours (how long it stays in your system)
- FDA application
- ANDA202244
- Availability
- Discontinued (per FDA)
Storing Rizatriptan Benzoate, and how long it keeps
Quoted from this product’s own FDA label. Storage belongs to the product and its device, not to the drug in general — a pen and a tablet of the same medicine are kept completely differently.
- “Store rizatriptan benzoate tablets USP at 20° to 25°C (68° to 77°F) [see USP Controlled Room Temperature].”
- “Store rizatriptan benzoate orally disintegrating tablets USP at 20° to 25°C (68° to 77°F) [see USP Controlled Room Temperature].”
- “Store rizatriptan benzoate tablets, USP at 20° to 25°C (68° to 77°F) [see USP Controlled Room Temperature].”
- “Store rizatriptan benzoate tablets at 20° to 25°C (68° to 77°F) [see USP Controlled Room Temperature].”
- “Store rizatriptan benzoate tablets at 20 o to 25 o C (68 o to 77 o F) [see USP Controlled Room Temperature].”
How long does Rizatriptan Benzoate stay in your body?
The elimination half-life of rizatriptan benzoate is about 2 to 3 hours — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. The label states the plasma half-life of rizatriptan averages 2-3 hours in both males and females. Rizatriptan has one active metabolite, N-monodesmethyl-rizatriptan, but it does not outlast the parent drug: plasma levels are only about 14% of the parent's and the label says it "is eliminated at a similar rate," so it does not meaningfully extend how long the drug stays in the body. Half-life is not restated for special populations, but exposure (AUC) shifts: it was unchanged in mild-to-moderate renal impairment (CrCl 10-60 mL/min/1.73 m2) and about 44% higher in hemodialysis patients (CrCl <2 mL/min/1.73 m2); it was similar in mild hepatic impairment and about 30% higher in moderate hepatic impairment from alcoholic cirrhosis. Pharmacokinetics in healthy adults aged 65-77 were similar to those in adults aged 18-45, so age alone does not change it. AUC is about 30% higher in females than males. There is no extended-release rizatriptan; MAXALT-MLT orally disintegrating tablets have similar bioavailability and peak levels to regular tablets, only slower absorption (Tmax delayed). Two interactions raise exposure sharply: propranolol increased rizatriptan AUC by 70%, and an MAO-A inhibitor increased rizatriptan AUC 119% and the active metabolite's AUC by more than 400%.
This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: MAXALT (rizatriptan benzoate) tablets / MAXALT-MLT orally disintegrating tablets — FDA prescribing information, Clinical Pharmacology (Pharmacokinetics).
Drug class
How this class works, per Triptans - StatPearls - NCBI Bookshelf.
May treat (source: NIH RxClass)
See how Rizatriptan Benzoate ranks — best-rated serotonin-1b and serotonin-1d receptor agonist for:
Dosage forms
Tablet and Tablet, orally disintegrating
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
Same active ingredient, far cheaper. Is there a generic? →
Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
Compare alternatives
A same-class option may cost less. See alternatives →
Frequently asked questions
- What does Rizatriptan Benzoate treat?
- Rizatriptan Benzoate (Rizatriptan Benzoate) may be used to treat migraine disorders, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
- How does Rizatriptan Benzoate work?
- Rizatriptan Benzoate is a serotonin-1b and serotonin-1d receptor agonist. These migraine drugs (triptans) switch on serotonin 5-HT1B/1D receptors: they tighten the dilated blood vessels around the brain and quiet the trigeminal nerve pathway, blocking the release of pain-signaling molecules that drive a migraine attack.
- How is Rizatriptan Benzoate rated?
- pharmaranks gives Rizatriptan Benzoate a composite score of 3.3 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
- Is there a coupon or discount for Rizatriptan Benzoate?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Rizatriptan Benzoate. To pay less, Rizatriptan Benzoate is already a generic — usually the lowest-cost version — so the main levers are comparing cash prices between pharmacies and using a pharmacy discount-card service. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Rizatriptan Benzoate?
- Rizatriptan Benzoate is marketed by Apotex. You can see Apotex's full profile, rating, and other products on pharmaranks.
- Is Rizatriptan Benzoate a brand-name or generic drug?
- Rizatriptan Benzoate is a generic medication; its active ingredient is Rizatriptan Benzoate. Generics contain the same active ingredient as the brand-name original and are usually lower cost.
- Is Rizatriptan Benzoate available over the counter?
- No. Rizatriptan Benzoate is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Rizatriptan Benzoate come in?
- Rizatriptan Benzoate is currently marketed as tablet and tablet, orally disintegrating, per the FDA's National Drug Code Directory.
- What class of drug is Rizatriptan Benzoate?
- Rizatriptan Benzoate is classified as serotonin-1b and serotonin-1d receptor agonist, per the FDA's Established Pharmacologic Class.
- Is Rizatriptan Benzoate FDA-registered?
- Rizatriptan Benzoate is on record with the U.S. FDA under application number ANDA202244. You can verify this on its official FDA label.
- Has Rizatriptan Benzoate been recalled by the FDA?
- Rizatriptan Benzoate has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
- Is Rizatriptan Benzoate safe?
- There's no single safe-or-not verdict. pharmaranks gives Rizatriptan Benzoate a recall-safety score of 66/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.
Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
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rizatriptan benzoate
66/100