quillichew er
Quillichew ER (Methylphenidate Hydrochloride) is a central nervous system stimulant used to treat Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Narcolepsy.
Methylphenidate Hydrochloride · by Nextwave
Available as a generic: Methylphenidate Hydrochloride
⚠ FDA reports a current shortage of the tablet form — availability differs between suppliers — see drug shortages →Key facts
- Active ingredient
- Methylphenidate Hydrochloride
- Drug class
- Central Nervous System Stimulant
- Form
- Tablet, chewable, extended release
- Strength
- Methylphenidate Hydrochloride 20MG · Methylphenidate Hydrochloride 30MG · Methylphenidate Hydrochloride 40MG
- Type
- Prescription (Rx)
- Brand or generic
- Brand-name
- Manufacturer
- Nextwave
- Half-life
- about 2.7 hours (how long it stays in your system)
- What the pharmacy pays
- ~$18.94 for 30 — not your price
- FDA application
- NDA207960
How long does Methylphenidate Hydrochloride stay in your body?
The elimination half-life of methylphenidate hydrochloride is about 2.7 hours — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the terminal elimination half-life of immediate-release methylphenidate in adults; the main metabolite (ritalinic acid) has little or no activity and does not extend the drug's action. Extended-release brands like Concerta and Ritalin LA don't change the molecule's true half-life — they only release it slowly, so their longer apparent duration comes from the delivery system, not slower elimination.
This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: METHYLPHENIDATE HYDROCHLORIDE oral solution (DailyMed FDA label).
Drug class
How this class works, per Stimulants — StatPearls, NCBI Bookshelf (NIH).
May treat (source: NIH RxClass)
See how Quillichew ER ranks — best-rated central nervous system stimulant for:
Dosage forms
Tablet, chewable, extended release
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
Same active ingredient, far cheaper. Is there a generic? →
Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
Compare alternatives
A same-class option may cost less. See alternatives →
Frequently asked questions
- What does Quillichew ER treat?
- Quillichew ER (Methylphenidate Hydrochloride) may be used to treat attention deficit disorder with hyperactivity, depressive disorder, narcolepsy, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
- How does Quillichew ER work?
- Quillichew ER is a central nervous system stimulant. CNS stimulants raise the levels of the brain's signaling chemicals dopamine and norepinephrine, either by releasing more of them or by blocking their reuptake. This heightened activity in attention and arousal circuits increases alertness, energy, and focus.
- How much does Quillichew ER cost?
- Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $18.94 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins. Pharmacies pay less for a same-class option, Cafcit — about $2.55 on the same basis.
- Is there a coupon or discount for Quillichew ER?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Quillichew ER. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Quillichew ER?
- Quillichew ER is marketed by Nextwave. You can see Nextwave's full profile, rating, and other products on pharmaranks.
- Is Quillichew ER a brand-name or generic drug?
- Quillichew ER is a brand-name product with the active ingredient Methylphenidate Hydrochloride. Lower-cost generic equivalents containing Methylphenidate Hydrochloride are available — ask your pharmacist.
- Is Quillichew ER available over the counter?
- No. Quillichew ER is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Quillichew ER come in?
- Quillichew ER is currently marketed as tablet, chewable, extended release, per the FDA's National Drug Code Directory.
- What class of drug is Quillichew ER?
- Quillichew ER is classified as central nervous system stimulant, per the FDA's Established Pharmacologic Class.
- Is Quillichew ER FDA-registered?
- Quillichew ER is on record with the U.S. FDA under application number NDA207960. You can verify this on its official FDA label.
Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
What people report to the FDA about METHYLPHENIDATE HYDROCHLORIDE
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 25,782 reports naming METHYLPHENIDATE HYDROCHLORIDE — the active ingredient in Quillichew ER, and the FDA flagged 64% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- fatigue1,334 reports
- headache1,314 reports
- anxiety1,303 reports
- nausea1,227 reports
- insomnia922 reports
- depression916 reports
- somnolence887 reports
- dizziness842 reports
Read these as a signal, not a rate. A report does not mean METHYLPHENIDATE HYDROCHLORIDE caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.
Source: openFDA drug/event (FAERS), retrieved September 25, 2026.
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