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adzenys xr-odt

Adzenys XR-ODT (Amphetamine) is a central nervous system stimulant used to treat Attention Deficit Disorder with Hyperactivity, Narcolepsy.

Amphetamine · by Neos Theraps Inc

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass
Lower-cost optionsSave up to 99%
This medication~$478.55/30
Cheapest in class · cafcit~$2.55/30
See FDA-approved alternatives

Key facts

Active ingredient
Amphetamine
Form
Tablet, orally disintegrating
Strength
Amphetamine EQ 12.5MG Base · Amphetamine EQ 15.7MG Base · Amphetamine EQ 18.8MG Base · Amphetamine EQ 3.1MG Base · Amphetamine EQ 6.3MG Base · Amphetamine EQ 9.4MG Base
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Neos Theraps Inc
Half-life
about 10 to 11 hours for d-amphetamine (range 9.8 to 11 hours) and about 12 to 14 hours for l-amphetamine (range 11.5 to 13.8 hours) in healthy adults (how long it stays in your system)
What the pharmacy pays
~$478.55 for 30 — not your price
FDA application
NDA204326

How long does Amphetamine stay in your body?

The elimination half-life of amphetamine is about 10 to 11 hours for d-amphetamine (range 9.8 to 11 hours) and about 12 to 14 hours for l-amphetamine (range 11.5 to 13.8 hours) in healthy adults — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. These are elimination half-lives for the two amphetamine isomers themselves; l-amphetamine clears more slowly than d-amphetamine. Elimination speeds up in acidic urine and slows in alkaline urine, and can be prolonged by kidney or liver problems.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: Adderall (dextroamphetamine and amphetamine) CII tablet — FDA/DailyMed label, Clinical Pharmacology.

Drug class

How this class works, per Stimulants — StatPearls, NCBI Bookshelf (NIH).

May treat (source: NIH RxClass)

See how Adzenys XR-ODT ranks — best-rated central nervous system stimulant for:

Dosage forms

Tablet, orally disintegrating

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

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Request a 90-day supply

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Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

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Frequently asked questions

What does Adzenys XR-ODT treat?
Adzenys XR-ODT (Amphetamine) may be used to treat attention deficit disorder with hyperactivity, narcolepsy, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Adzenys XR-ODT work?
Adzenys XR-ODT is a central nervous system stimulant. CNS stimulants raise the levels of the brain's signaling chemicals dopamine and norepinephrine, either by releasing more of them or by blocking their reuptake. This heightened activity in attention and arousal circuits increases alertness, energy, and focus.
How much does Adzenys XR-ODT cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $478.55 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins. Pharmacies pay less for a same-class option, Cafcit — about $2.55 on the same basis.
Is there a coupon or discount for Adzenys XR-ODT?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Adzenys XR-ODT. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Adzenys XR-ODT?
Adzenys XR-ODT is marketed by Neos Theraps Inc. You can see Neos Theraps Inc's full profile, rating, and other products on pharmaranks.
Is Adzenys XR-ODT a brand-name or generic drug?
Adzenys XR-ODT is a brand-name product with the active ingredient Amphetamine.
Is Adzenys XR-ODT available over the counter?
No. Adzenys XR-ODT is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Adzenys XR-ODT come in?
Adzenys XR-ODT is currently marketed as tablet, orally disintegrating, per the FDA's National Drug Code Directory.
What class of drug is Adzenys XR-ODT?
Adzenys XR-ODT is classified as central nervous system stimulant, per the FDA's Established Pharmacologic Class.
Is Adzenys XR-ODT FDA-registered?
Adzenys XR-ODT is on record with the U.S. FDA under application number NDA204326. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

What people report to the FDA about AMPHETAMINE

The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 15,161 reports naming AMPHETAMINE — the active ingredient in Adzenys XR-ODT, and the FDA flagged 67% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:

  • headache805 reports
  • fatigue795 reports
  • nausea630 reports
  • anxiety606 reports
  • somnolence552 reports
  • drug diversion516 reports
  • disturbance in attention484 reports
  • feeling abnormal472 reports

Read these as a signal, not a rate. A report does not mean AMPHETAMINE caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.

Source: openFDA drug/event (FAERS), retrieved September 25, 2026.

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