protopam chloride
Protopam Chloride (Pralidoxime Chloride) is a medication used to treat Poisoning, Drug Overdose, Drug-Related Side Effects and Adverse Reactions.
Pralidoxime Chloride · by Wyeth Ayerst
Key facts
- Active ingredient
- Pralidoxime Chloride
- Form
- Injectable
- Strength
- Pralidoxime Chloride 500MG
- Type
- Prescription (Rx)
- Brand or generic
- Brand-name
- Manufacturer
- Wyeth Ayerst
- FDA application
- NDA014122
- Availability
- Discontinued (per FDA)
May treat (source: NIH RxClass)
Dosage forms
Injectable
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
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Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
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Frequently asked questions
- What does Protopam Chloride treat?
- Protopam Chloride (Pralidoxime Chloride) may be used to treat poisoning, drug overdose, drug-related side effects and adverse reactions, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
- Is there a coupon or discount for Protopam Chloride?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Protopam Chloride. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Protopam Chloride?
- Protopam Chloride is marketed by Wyeth Ayerst. You can see Wyeth Ayerst's full profile, rating, and other products on pharmaranks.
- Is Protopam Chloride a brand-name or generic drug?
- Protopam Chloride is a brand-name product with the active ingredient Pralidoxime Chloride.
- Is Protopam Chloride available over the counter?
- No. Protopam Chloride is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Protopam Chloride come in?
- Protopam Chloride is currently marketed as injectable, per the FDA's National Drug Code Directory.
- Is Protopam Chloride FDA-registered?
- Protopam Chloride is on record with the U.S. FDA under application number NDA014122. You can verify this on its official FDA label.
Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
What people report to the FDA about PRALIDOXIME CHLORIDE
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 30 reports naming PRALIDOXIME CHLORIDE — the active ingredient in Protopam Chloride, and the FDA flagged 67% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- accidental exposure9 reports
- expired drug administered5 reports
- injection site injury4 reports
- heart rate increased3 reports
- injection site pain3 reports
- arthralgia2 reports
- blood pressure fluctuation2 reports
- cerebrovascular accident2 reports
Read these as a signal, not a rate. A report does not mean PRALIDOXIME CHLORIDE caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.
Source: openFDA drug/event (FAERS), retrieved September 26, 2026.
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