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probuphine

Probuphine (Buprenorphine Hydrochloride) is a partial opioid agonist used to treat Heroin Dependence, Pain.

Buprenorphine Hydrochloride · by Reacx Pharms

Available as a generic: Buprenorphine Hydrochloride

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Form
Implant
Strength
Buprenorphine Hydrochloride EQ 80MG BASE/IMPLANT
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Reacx Pharms
What the pharmacy pays
~$683.94 for 30 — not your price
FDA application
NDA204442
Availability
Discontinued (per FDA)

Drug class

May treat (source: NIH RxClass)

See how Probuphine ranks — best-rated partial opioid agonist for:

Dosage forms

Implant

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Probuphine treat?
Probuphine (Buprenorphine Hydrochloride) may be used to treat heroin dependence, pain, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How much does Probuphine cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $683.94 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for Probuphine?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Probuphine. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Probuphine?
Probuphine is marketed by Reacx Pharms. You can see Reacx Pharms's full profile, rating, and other products on pharmaranks.
Is Probuphine a brand-name or generic drug?
Probuphine is a brand-name product with the active ingredient Buprenorphine Hydrochloride. Lower-cost generic equivalents containing Buprenorphine Hydrochloride are available — ask your pharmacist.
Is Probuphine available over the counter?
No. Probuphine is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Probuphine come in?
Probuphine is currently marketed as implant, per the FDA's National Drug Code Directory.
What class of drug is Probuphine?
Probuphine is classified as partial opioid agonist, per the FDA's Established Pharmacologic Class.
Is Probuphine FDA-registered?
Probuphine is on record with the U.S. FDA under application number NDA204442. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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