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PROBUPHINE vs SUBLOCADE

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. PROBUPHINE and SUBLOCADE are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

probuphinesublocade

Rating

New
New

Pharmacy pays

~$683.94 /30
~$683.94 /30

Type

RX
RX

Active ingredient

BUPRENORPHINE HYDROCHLORIDE
BUPRENORPHINE

Manufacturer

Reacx Pharms
Indivior

Dosage forms

Implant
Solution

Drug class

Partial Opioid Agonist
Partial Opioid Agonist

Boxed warning

None
Boxed warning

Treats

Heroin Dependence, Pain
Heroin Dependence, Pain

Frequently asked questions

Which is cheaper, Probuphine or Sublocade?

Pharmacies pay about the same to acquire either one — roughly $683.94 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Probuphine and Sublocade?

Probuphine contains Buprenorphine Hydrochloride, while Sublocade contains Buprenorphine — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.