poly-pred

How long does Neomycin Sulfate and Polymyxin B Sulfate and Prednisolone Acetate stay in your body?

The elimination half-life of neomycin sulfate and polymyxin b sulfate and prednisolone acetate is 2 to 4 hours — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the plasma (elimination) half-life; the label states prednisolone "is eliminated from the plasma with a half-life of 2 to 4 hours" and is 70-90% protein bound. Prednisolone is itself the active corticosteroid (prednisone is the prodrug that is converted to prednisolone in the liver), so no active metabolite outlasts it. Its biological/anti-inflammatory effect lasts much longer than the plasma half-life — prednisolone is an intermediate-acting glucocorticoid with a tissue effect of roughly 18-36 hours, which is why once-daily dosing works. It is metabolized mainly in the liver, so clearance can be slowed and the half-life prolonged in significant liver impairment. Note that the plasma half-life is not the same as a drug-test detection window.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: PediaPred (prednisolone sodium phosphate) oral solution — FDA label via DailyMed.

Frequently asked questions

How is Poly-Pred rated?

pharmaranks gives Poly-Pred a composite score of 3.6 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.

How much does Poly-Pred cost?

Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $25.36 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.

Is there a coupon or discount for Poly-Pred?

pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Poly-Pred. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.

Who makes Poly-Pred?

Poly-Pred is marketed by Allergan. You can see Allergan's full profile, rating, and other products on pharmaranks.

Is Poly-Pred a brand-name or generic drug?

Poly-Pred is a brand-name product with the active ingredient Neomycin Sulfate and Polymyxin B Sulfate and Prednisolone Acetate.

Is Poly-Pred available over the counter?

No. Poly-Pred is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.

What forms does Poly-Pred come in?

Poly-Pred is currently marketed as drops, per the FDA's National Drug Code Directory.

Is Poly-Pred FDA-registered?

Poly-Pred is on record with the U.S. FDA under application number NDA050081. You can verify this on its official FDA label.

Has Poly-Pred been recalled by the FDA?

Poly-Pred has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.

Is Poly-Pred safe?

There's no single safe-or-not verdict. pharmaranks gives Poly-Pred a recall-safety score of 72/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.