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Pharmaranks rates Permax 3.7/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Permax (Pergolide Mesylate) is a medication used to treat Tourette Syndrome, Parkinson Disease.

Pergolide Mesylate · by Valeant Pharm Intl

74/100Limited · 1 source

Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →

Rated against independent regulatory sources·Last updated October 10, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Pergolide Mesylate
Form
Tablet
Strength
Pergolide Mesylate EQ 0.05MG Base · Pergolide Mesylate EQ 0.25MG Base · Pergolide Mesylate EQ 1MG Base
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Valeant Pharm Intl
FDA application
NDA019385
Availability
Discontinued (per FDA)

May treat (source: NIH RxClass)

Dosage forms

Tablet

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

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Frequently asked questions

What does Permax treat?
Permax (Pergolide Mesylate) may be used to treat tourette syndrome, parkinson disease, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How is Permax rated?
pharmaranks gives Permax a composite score of 3.7 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
Is there a coupon or discount for Permax?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Permax. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Permax?
Permax is marketed by Valeant Pharm Intl. You can see Valeant Pharm Intl's full profile, rating, and other products on pharmaranks.
Is Permax a brand-name or generic drug?
Permax is a brand-name product with the active ingredient Pergolide Mesylate.
Is Permax available over the counter?
No. Permax is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Permax come in?
Permax is currently marketed as tablet, per the FDA's National Drug Code Directory.
Is Permax FDA-registered?
Permax is on record with the U.S. FDA under application number NDA019385. You can verify this on its official FDA label.
Has Permax been recalled by the FDA?
Permax has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
Is Permax safe?
There's no single safe-or-not verdict. pharmaranks gives Permax a recall-safety score of 74/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

What people report to the FDA about PERGOLIDE MESYLATE

The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 252 reports naming PERGOLIDE MESYLATE — the active ingredient in Permax, and the FDA flagged 96% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:

  • mitral valve incompetence45 reports
  • aortic valve incompetence41 reports
  • cardiac valve disease31 reports
  • dyspnoea27 reports
  • tricuspid valve incompetence25 reports
  • cardiac failure23 reports
  • mitral valve disease20 reports
  • pathological gambling19 reports

Read these as a signal, not a rate. A report does not mean PERGOLIDE MESYLATE caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.

Source: openFDA drug/event (FAERS), retrieved September 25, 2026.

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