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percodan-demi

Percodan-Demi is a combination medicine containing Aspirin, Oxycodone Hydrochloride, and Oxycodone Terephthalate.

Aspirin and Oxycodone Hydrochloride and Oxycodone Terephthalate · by Endo Operations

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Aspirin and Oxycodone Hydrochloride and Oxycodone Terephthalate
Form
Tablet
Strength
Aspirin 325MG; Oxycodone Hydrochloride 2.25MG; Oxycodone Terephthalate 0.19MG **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons**
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Endo Operations
Half-life
about 3.5 to 4 hours (how long it stays in your system)
What the pharmacy pays
~$0.78 for 30 — not your price
FDA application
NDA007337
Availability
Discontinued (per FDA)

How long does Aspirin and Oxycodone Hydrochloride and Oxycodone Terephthalate stay in your body?

The elimination half-life of aspirin and oxycodone hydrochloride and oxycodone terephthalate is about 3.5 to 4 hours — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the elimination half-life for immediate-release oxycodone in adults with normal organ function; extended/controlled-release products act longer, and in kidney or liver impairment oxycodone concentrations run higher and clearance is reduced. The main metabolites (noroxycodone, oxymorphone) are not longer-acting than the parent drug for immediate-release oxycodone.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: OXYCODONE HYDROCHLORIDE tablet — DailyMed.

Dosage forms

Tablet

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

How much does Percodan-Demi cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.78 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for Percodan-Demi?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Percodan-Demi. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Percodan-Demi?
Percodan-Demi is marketed by Endo Operations. You can see Endo Operations's full profile, rating, and other products on pharmaranks.
Is Percodan-Demi a brand-name or generic drug?
Percodan-Demi is a brand-name product with the active ingredient Aspirin and Oxycodone Hydrochloride and Oxycodone Terephthalate.
Is Percodan-Demi available over the counter?
No. Percodan-Demi is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Percodan-Demi come in?
Percodan-Demi is currently marketed as tablet, per the FDA's National Drug Code Directory.
Is Percodan-Demi FDA-registered?
Percodan-Demi is on record with the U.S. FDA under application number NDA007337. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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