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Pharmaranks rates Oforta 3.5/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Oforta (Fludarabine Phosphate) is a nucleoside metabolic inhibitor used to treat Non-Hodgkin Lymphoma, B-Cell Chronic Lymphocytic Leukemia.

Fludarabine Phosphate · by Sanofi Aventis US

70/100Limited · 1 source

Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →

Rated against independent regulatory sources·Last updated October 10, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Fludarabine Phosphate
Form
Tablet
Strength
Fludarabine Phosphate 10MG
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Sanofi Aventis US
FDA application
NDA022273
Availability
Discontinued (per FDA)

Drug class

How this class works, per Gemcitabine — LiverTox, NCBI Bookshelf (NIH).

May treat (source: NIH RxClass)

Dosage forms

Tablet

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Oforta treat?
Oforta (Fludarabine Phosphate) may be used to treat non-hodgkin lymphoma, b-cell chronic lymphocytic leukemia, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Oforta work?
Oforta is a nucleoside metabolic inhibitor. Nucleoside metabolic inhibitors are fake DNA building blocks that fast-dividing cancer cells mistake for the real thing. Once inside, they get incorporated into the cell's DNA and also block enzymes such as ribonucleotide reductase, which together halt DNA copying and cause the cancer cell to die.
How is Oforta rated?
pharmaranks gives Oforta a composite score of 3.5 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
Is there a coupon or discount for Oforta?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Oforta. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Oforta?
Oforta is marketed by Sanofi Aventis US. You can see Sanofi Aventis US's full profile, rating, and other products on pharmaranks.
Is Oforta a brand-name or generic drug?
Oforta is a brand-name product with the active ingredient Fludarabine Phosphate.
Is Oforta available over the counter?
No. Oforta is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Oforta come in?
Oforta is currently marketed as tablet, per the FDA's National Drug Code Directory.
What class of drug is Oforta?
Oforta is classified as nucleoside metabolic inhibitor, per the FDA's Established Pharmacologic Class.
Is Oforta FDA-registered?
Oforta is on record with the U.S. FDA under application number NDA022273. You can verify this on its official FDA label.
Has Oforta been recalled by the FDA?
Oforta has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
Is Oforta safe?
There's no single safe-or-not verdict. pharmaranks gives Oforta a recall-safety score of 70/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

What people report to the FDA about FLUDARABINE PHOSPHATE

The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 11,055 reports naming FLUDARABINE PHOSPHATE — the active ingredient in Oforta, and the FDA flagged 98% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:

  • pyrexia961 reports
  • febrile neutropenia833 reports
  • neutropenia602 reports
  • cytokine release syndrome507 reports
  • cytomegalovirus infection491 reports
  • sepsis460 reports
  • pancytopenia432 reports
  • acute graft versus host disease420 reports

Read these as a signal, not a rate. A report does not mean FLUDARABINE PHOSPHATE caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.

Source: openFDA drug/event (FAERS), retrieved September 25, 2026.

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