Nucleoside Metabolic Inhibitor drugs compared
Compare all 13 Nucleoside Metabolic Inhibitor drugs side by side, used for conditions such as leukemia, lymphoma, meningeal neoplasms. They share one FDA-defined mechanism but differ in approved uses, prescription status, brand-vs-generic options, price, and FDA recall-safety record — which our independent rating scores. The highest-rated is cytarabine.
Top-rated nucleoside metabolic inhibitor: 1. Cytarabine · 2. Tolak · 3. Azacitidine
| Drug | Generic | Form | Status | Used for | Safety ratingFDA recall-based | Pharmacy pays |
|---|---|---|---|---|---|---|
| Cytarabine | — | Injectable | Prescription | Leukemia, Lymphoma | 72/100 | — |
| Tolak | Fluorouracil | Topical | Prescription | Breast Neoplasms, Basal Cell Carcinoma | 72/100 | $1 |
| Azacitidine | — | Injectable | Prescription | Anemia, Refractory, Anemia, Sideroblastic | 70/100 | — |
| Arranon | Nelarabine | Injectable | Prescription | Leukemia, T-Cell | 68/100 | — |
| Capecitabine | — | Tablet | Prescription | Breast Neoplasms, Colorectal Neoplasms | Not yet rated | $14 |
| Decitabine | — | Injectable | Prescription | Myelodysplastic Syndromes | Not yet rated | — |
| Efudex | Fluorouracil | Topical | Prescription | Breast Neoplasms, Basal Cell Carcinoma | Not yet rated | $1 |
| Favlyxa | Fluorouracil | Injectable | Prescription | Breast Neoplasms, Basal Cell Carcinoma | Not yet rated | $1 |
| Fluorouracil | — | Topical | Prescription | Breast Neoplasms, Basal Cell Carcinoma | Not yet rated | $1 |
| Inlexzo | Gemcitabine Hydrochloride | System | Prescription | Breast Neoplasms, Carcinoma, Non-Small-Cell Lung | Not yet rated | $600 |
| Nelarabine | — | Injectable | Prescription | Leukemia, T-Cell | Not yet rated | — |
| Onureg | Azacitidine | Tablet | Prescription | Anemia, Refractory, Anemia, Sideroblastic | Not yet rated | — |
The safety rating column is unique to pharmaranks — an independent 0–100 score from FDA regulatory recall data. Higher is safer. Not medical advice.
Best nucleoside metabolic inhibitor by condition
Full ranking · 13 drugs
- 172/100
cytarabine
Cytarabine
- 272/100
tolak
Fluorouracil
- 370/100
azacitidine
Azacitidine
- 468/100
arranon
Nelarabine
- 5New
capecitabine
Capecitabine
- 6New
decitabine
Decitabine
- 7New
efudex
Fluorouracil
- 8New
favlyxa
Fluorouracil
- 9New
fluorouracil
Fluorouracil
- 10New
inlexzo
Gemcitabine Hydrochloride
- 11New
nelarabine
Nelarabine
- 12New
onureg
Azacitidine
- 13New
vidaza
Azacitidine
Frequently asked questions
What is the Nucleoside Metabolic Inhibitor drug class?
Nucleoside Metabolic Inhibitor is an FDA Established Pharmacologic Class (EPC) — a group of drugs that share a mechanism of action. pharmaranks lists 13 Nucleoside Metabolic Inhibitor products, each independently rated.
Are all Nucleoside Metabolic Inhibitor drugs the same?
No. Nucleoside Metabolic Inhibitor drugs share the same core mechanism — that is why they sit in one FDA class — but they differ in their approved uses, available forms, whether they are prescription or over-the-counter, brand-vs-generic options and price, and their FDA recall-safety record.
What conditions do Nucleoside Metabolic Inhibitor drugs treat?
Per NIH RxClass drug-classification data, Nucleoside Metabolic Inhibitor drugs are used for conditions including leukemia, lymphoma, meningeal neoplasms, breast neoplasms, basal cell carcinoma, colonic neoplasms.
Which Nucleoside Metabolic Inhibitor drug is best-rated?
By our independent rating, cytarabine currently ranks highest among Nucleoside Metabolic Inhibitor drugs. Ratings are based on FDA regulatory (recall-safety) data — always consult a professional.
Sources: the Nucleoside Metabolic Inhibitor class definition and its member drugs come from the U.S. NLM RxClass (Established Pharmacologic Class); how the class works is summarized from Gemcitabine — LiverTox, NCBI Bookshelf (NIH). Ratings are pharmaranks’ independent FDA recall-safety analysis.