neptazane
Neptazane (Methazolamide) is a medication used to treat Open-Angle Glaucoma, Angle-Closure Glaucoma.
Methazolamide · by Lederle
Pharmacy acquisition cost fell 16% — $1.1790 → $0.9850 per ea (CMS NADAC)source
Key facts
- Active ingredient
- Methazolamide
- Form
- Tablet
- Strength
- Methazolamide 25MG **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons** · Methazolamide 50MG **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons**
- Type
- Prescription (Rx)
- Brand or generic
- Brand-name
- May treat
- open-angle glaucoma, angle-closure glaucoma
- Manufacturer
- Lederle
- What the pharmacy pays
- ~$29.55 for 30 — not your price
- FDA application
- NDA011721
- Availability
- Discontinued (per FDA)
May treat (source: NIH RxClass)
Dosage forms
Tablet
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
Same active ingredient, far cheaper. Is there a generic? →
Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
Compare alternatives
A same-class option may cost less. See alternatives →
Frequently asked questions
- What does Neptazane treat?
- Neptazane (Methazolamide) may be used to treat open-angle glaucoma, angle-closure glaucoma, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
- How much does Neptazane cost?
- Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $29.55 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
- Is there a coupon or discount for Neptazane?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Neptazane. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Neptazane?
- Neptazane is marketed by Lederle. You can see Lederle's full profile, rating, and other products on pharmaranks.
- Is Neptazane a brand-name or generic drug?
- Neptazane is a brand-name product with the active ingredient Methazolamide.
- Is Neptazane available over the counter?
- No. Neptazane is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Neptazane come in?
- Neptazane is currently marketed as tablet, per the FDA's National Drug Code Directory.
- Is Neptazane FDA-registered?
- Neptazane is on record with the U.S. FDA under application number NDA011721. You can verify this on its official FDA label.
Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
What people report to the FDA about METHAZOLAMIDE
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 356 reports naming METHAZOLAMIDE — the active ingredient in Neptazane, and the FDA flagged 63% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- fatigue43 reports
- dizziness29 reports
- dyspnoea29 reports
- headache29 reports
- blood pressure increased23 reports
- asthenia22 reports
- anxiety20 reports
- diarrhoea20 reports
Read these as a signal, not a rate. A report does not mean METHAZOLAMIDE caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.
Source: openFDA drug/event (FAERS), retrieved September 25, 2026.
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