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jadelle

Jadelle (Levonorgestrel) is a progestin.

Levonorgestrel · by Population Council

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass
Lower-cost optionsSave up to 96%
This medication~$192.31/30
Cheapest in class · megestrol acetate~$7.14/30
See FDA-approved alternatives

Key facts

Active ingredient
Levonorgestrel
Drug class
Progestin
Form
Implant
Strength
Levonorgestrel 75MG/IMPLANT **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons**
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Population Council
Half-life
about 36 hours (36 ± 13 hours at steady state) (how long it stays in your system)
What the pharmacy pays
~$192.31 for 30 — not your price
FDA application
NDA020544
Availability
Discontinued (per FDA)

How long does Levonorgestrel stay in your body?

The elimination half-life of levonorgestrel is about 36 hours (36 ± 13 hours at steady state) — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. This is the terminal elimination half-life stated directly for levonorgestrel; the label reports no active metabolite that outlasts the parent, and levonorgestrel is not a prodrug. The number comes from a levonorgestrel/ethinyl estradiol combination oral-contraceptive label (Aviane), where it is attributed specifically to the levonorgestrel component; the single-ingredient OTC emergency-contraceptive labels do not state a half-life. On populations: the label says no formal studies evaluated hepatic or renal impairment, but cautions that steroid hormones may be poorly metabolized in patients with impaired liver function; it notes no apparent pharmacokinetic differences across races, and states nothing about older adults.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: Aviane (levonorgestrel and ethinyl estradiol) label — DailyMed, Clinical Pharmacology / Pharmacokinetics.

Drug class

  • Progestin
  • Progestin-containing Intrauterine System

How this class works, per Progestins - StatPearls - NCBI Bookshelf.

Dosage forms

Implant

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

How does Jadelle work?
Jadelle is a progestin. Progestins are lab-made versions of the hormone progesterone. Acting through progesterone receptors, they quiet the brain signals that trigger ovulation, thicken cervical mucus so sperm cannot pass, and thin the uterine lining, which together help prevent pregnancy and regulate periods.
How much does Jadelle cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $192.31 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins. Pharmacies pay less for a same-class option, Megestrol Acetate — about $7.14 on the same basis.
Is there a coupon or discount for Jadelle?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Jadelle. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Jadelle?
Jadelle is marketed by Population Council. You can see Population Council's full profile, rating, and other products on pharmaranks.
Is Jadelle a brand-name or generic drug?
Jadelle is a brand-name product with the active ingredient Levonorgestrel.
Is Jadelle available over the counter?
No. Jadelle is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Jadelle come in?
Jadelle is currently marketed as implant, per the FDA's National Drug Code Directory.
What class of drug is Jadelle?
Jadelle is classified as progestin, progestin-containing intrauterine system, per the FDA's Established Pharmacologic Class.
Is Jadelle FDA-registered?
Jadelle is on record with the U.S. FDA under application number NDA020544. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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