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eldepryl

Eldepryl (Selegiline Hydrochloride) is a monoamine oxidase inhibitor used to treat Alzheimer Disease, Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Parkinson Disease.

Selegiline Hydrochloride · by Quagen

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass
~$19.71 /30
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Lower-cost optionsSave up to 11%
This medication~$19.71/30
Cheapest in class · nardil~$17.62/30
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Key facts

Active ingredient
Selegiline Hydrochloride
Form
Capsule
Strength
Selegiline Hydrochloride 5MG **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons**
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Quagen
What the pharmacy pays
~$19.71 for 30 — not your price
FDA application
NDA020647
Availability
Discontinued (per FDA)

Foods & drinks to be careful with

Well-established interactions for this medicine’s drug class, summarized from public health authorities. General information, not medical advice — always confirm with your pharmacist or the label.

  • Tyramine-rich foods

    Watch out for: aged cheeses, cured or fermented meats, sauerkraut, soy sauce, tap/unpasteurized beer, and other aged or fermented foods.

    MAO inhibitors block the enzyme that breaks down tyramine. Eating high-tyramine foods while on an MAOI can cause a dangerous spike in blood pressure (a hypertensive crisis).

    What to do: Follow the specific food list your prescriber gives you and avoid high-tyramine foods while taking an MAOI (and for a period after stopping). Seek urgent care for a sudden severe headache.

    Source: Phenelzine (an MAOI) — MedlinePlus (U.S. National Library of Medicine)

Drug class

May treat (source: NIH RxClass)

Dosage forms

Capsule

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Eldepryl treat?
Eldepryl (Selegiline Hydrochloride) may be used to treat alzheimer disease, attention deficit disorder with hyperactivity, depressive disorder, parkinson disease, schizophrenia, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How much does Eldepryl cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $19.71 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins. Pharmacies pay less for a same-class option, Nardil — about $17.62 on the same basis.
Is there a coupon or discount for Eldepryl?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Eldepryl. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Eldepryl?
Eldepryl is marketed by Quagen. You can see Quagen's full profile, rating, and other products on pharmaranks.
Is Eldepryl a brand-name or generic drug?
Eldepryl is a brand-name product with the active ingredient Selegiline Hydrochloride.
Is Eldepryl available over the counter?
No. Eldepryl is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Eldepryl come in?
Eldepryl is currently marketed as capsule, per the FDA's National Drug Code Directory.
What class of drug is Eldepryl?
Eldepryl is classified as monoamine oxidase inhibitor, monoamine oxidase type b inhibitor, per the FDA's Established Pharmacologic Class.
Is Eldepryl FDA-registered?
Eldepryl is on record with the U.S. FDA under application number NDA020647. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

What people report to the FDA about SELEGILINE HYDROCHLORIDE

The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 2,827 reports naming SELEGILINE HYDROCHLORIDE — the active ingredient in Eldepryl, and the FDA flagged 70% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:

  • hallucination277 reports
  • dyskinesia200 reports
  • fall199 reports
  • dizziness151 reports
  • tremor139 reports
  • confusional state131 reports
  • somnolence129 reports
  • insomnia117 reports

Read these as a signal, not a rate. A report does not mean SELEGILINE HYDROCHLORIDE caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.

Source: openFDA drug/event (FAERS), retrieved September 26, 2026.

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