ELDEPRYL vs EMSAM

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated June 7, 2026·How we rate

Possible drug interaction. ELDEPRYL and EMSAM are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	ELDEPRYL	EMSAM
Rating	New	New
Pharmacy pays	~$19.56 /30	~$19.56 /30
Type	RX	RX
Active ingredient	SELEGILINE HYDROCHLORIDE	SELEGILINE
Manufacturer	Quagen	Somerset
Dosage forms	Capsule	Patch
Drug class	Monoamine Oxidase Inhibitor	Monoamine Oxidase Inhibitor
Boxed warning	None	None
Treats	Alzheimer Disease, Attention Deficit Disorder with Hyperactivity, Depressive Disorder	Alzheimer Disease, Attention Deficit Disorder with Hyperactivity, Depressive Disorder

eldepryl emsam

Rating

New

Pharmacy pays

~$19.56 /30

Type

Active ingredient

SELEGILINE HYDROCHLORIDE

SELEGILINE

Manufacturer

Quagen

Somerset

Dosage forms

Capsule

Patch

Drug class

Monoamine Oxidase Inhibitor

Boxed warning

None

Treats

Alzheimer Disease, Attention Deficit Disorder with Hyperactivity, Depressive Disorder

Get eldeprylhigher-rated option

Advertising disclosure: Some links are affiliate links. We may earn a commission at no extra cost to you. This never affects our independent ratings.

Get treatment online

Licensed online providers — consult & get prescribed if eligible.

SesameCompare online visit prices

Frequently asked questions

Which is cheaper, Eldepryl or Emsam?

Pharmacies pay about the same to acquire either one — roughly $19.56 for a 30-count supply, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Eldepryl and Emsam?

Eldepryl contains Selegiline Hydrochloride, while Emsam contains Selegiline — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.