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cleocin hydrochloride

Pharmaranks rates Cleocin Hydrochloride 3.0/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Cleocin Hydrochloride (Clindamycin Hydrochloride) is a lincosamide antibacterial used to treat Acne Vulgaris, Actinomycetales Infections, Bacteroides Infections, Pneumocystis Pneumonia.

Clindamycin Hydrochloride · by Pfizer

Available as a generic: Clindamycin Hydrochloride

60/100Limited · 1 source

Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →

Rated against independent regulatory sources·Last updated October 10, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass
$0.18 /g
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Key facts

Active ingredient
Clindamycin Hydrochloride
Form
Capsule
Strength
Clindamycin Hydrochloride EQ 150MG Base · Clindamycin Hydrochloride EQ 300MG Base · Clindamycin Hydrochloride EQ 75MG Base
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Pfizer
Half-life
about 2.4 hours (how long it stays in your system)
What the pharmacy pays
~$0.18 per gm — not your price
FDA application
NDA050162

How long does Clindamycin Hydrochloride stay in your body?

The elimination half-life of clindamycin hydrochloride is about 2.4 hours — the time it takes the body to clear about half of it. As a rule of thumb, a medicine is mostly gone after roughly 4 to 5 half-lives, though this varies from person to person with age and kidney or liver function. The label gives an average biological (elimination) half-life of 2.4 hours for oral clindamycin hydrochloride, the active form. It runs slightly longer in older adults (about 4.0 hours, range 3.4–5.1, vs 3.2 hours, range 2.1–4.2, in younger adults) and is increased slightly in people with markedly reduced kidney or liver function. Clindamycin palmitate (oral pediatric solution) and clindamycin phosphate (injection) are inactive prodrugs that are hydrolyzed in the body to this same active clindamycin. Half-life reflects how fast the drug leaves the blood, not how long a drug test can detect it.

This is general information, not medical advice. It doesn’t tell you when a drug test would read negative (tests detect substances for different, often longer, windows) or when it’s safe to take another dose — ask your pharmacist or prescriber. Source: CLEOCIN HYDROCHLORIDE (clindamycin hydrochloride) capsule — FDA label, DailyMed.

Drug class

How this class works, per Clindamycin - StatPearls - NCBI Bookshelf.

May treat (source: NIH RxClass)

Dosage forms

Capsule

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Cleocin Hydrochloride treat?
Cleocin Hydrochloride (Clindamycin Hydrochloride) may be used to treat acne vulgaris, actinomycetales infections, bacteroides infections, pneumocystis pneumonia, staphylococcal infections, streptococcal infections, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Cleocin Hydrochloride work?
Cleocin Hydrochloride is a lincosamide antibacterial. Lincosamides such as clindamycin attach to the bacterial ribosome, the cell's protein-building machine, and stop it from linking amino acids together. Because the bacteria can no longer make the proteins they need, their growth is halted or, depending on the organism and dose, they are killed.
How is Cleocin Hydrochloride rated?
pharmaranks gives Cleocin Hydrochloride a composite score of 3.0 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
How much does Cleocin Hydrochloride cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.18 per gm, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for Cleocin Hydrochloride?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Cleocin Hydrochloride. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Cleocin Hydrochloride?
Cleocin Hydrochloride is marketed by Pfizer. You can see Pfizer's full profile, rating, and other products on pharmaranks.
Is Cleocin Hydrochloride a brand-name or generic drug?
Cleocin Hydrochloride is a brand-name product with the active ingredient Clindamycin Hydrochloride. Lower-cost generic equivalents containing Clindamycin Hydrochloride are available — ask your pharmacist.
Is Cleocin Hydrochloride available over the counter?
No. Cleocin Hydrochloride is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Cleocin Hydrochloride come in?
Cleocin Hydrochloride is currently marketed as capsule, per the FDA's National Drug Code Directory.
What class of drug is Cleocin Hydrochloride?
Cleocin Hydrochloride is classified as lincosamide antibacterial, per the FDA's Established Pharmacologic Class.
Is Cleocin Hydrochloride FDA-registered?
Cleocin Hydrochloride is on record with the U.S. FDA under application number NDA050162. You can verify this on its official FDA label.
Has Cleocin Hydrochloride been recalled by the FDA?
Cleocin Hydrochloride has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
Is Cleocin Hydrochloride safe?
There's no single safe-or-not verdict. pharmaranks gives Cleocin Hydrochloride a recall-safety score of 60/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

What people report to the FDA about CLINDAMYCIN HYDROCHLORIDE

The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 3,717 reports naming CLINDAMYCIN HYDROCHLORIDE — the active ingredient in Cleocin Hydrochloride, and the FDA flagged 78% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:

  • diarrhoea280 reports
  • rash274 reports
  • nausea247 reports
  • dyspnoea206 reports
  • drug hypersensitivity192 reports
  • pruritus181 reports
  • headache175 reports
  • fatigue159 reports

Read these as a signal, not a rate. A report does not mean CLINDAMYCIN HYDROCHLORIDE caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.

Source: openFDA drug/event (FAERS), retrieved September 25, 2026.

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