
caverject
Pharmaranks rates Caverject 3.0/5 for recall safety — an independent score from its FDA recall history and its manufacturer's record. Caverject (Alprostadil) is a prostaglandin analog used to treat Aortic Arch Syndromes, Aortic Coarctation, Patent Ductus Arteriosus, Pulmonary Hypertension.
Alprostadil · by Pfizer
Based on 1 source · Recall-safety score from FDA recall history — this product's own recalls and its manufacturer's record. Not an efficacy or quality rating. methodology →
Key facts
- Active ingredient
- Alprostadil
- Drug class
- Prostaglandin Analog
- Form
- Injectable
- Strength
- Alprostadil 0.005MG/ML · Alprostadil 0.01MG/ML · Alprostadil 0.02MG/ML
- Type
- Prescription (Rx)
- Brand or generic
- Brand-name
- Manufacturer
- Pfizer
- FDA application
- NDA020755
- Availability
- Discontinued (per FDA)
Drug class
- Prostaglandin Analog
- Prostaglandin E1 Agonist
How this class works, per Latanoprost - StatPearls - NCBI Bookshelf.
May treat (source: NIH RxClass)
- aortic arch syndromes
- aortic coarctation
- patent ductus arteriosus
- pulmonary hypertension
- pulmonary valve stenosis
- tetralogy of fallot
See how Caverject ranks — best-rated prostaglandin analog for:
Dosage forms
Injectable
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
Same active ingredient, far cheaper. Is there a generic? →
Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
Compare alternatives
A same-class option may cost less. See alternatives →
Frequently asked questions
- What does Caverject treat?
- Caverject (Alprostadil) may be used to treat aortic arch syndromes, aortic coarctation, patent ductus arteriosus, pulmonary hypertension, pulmonary valve stenosis, tetralogy of fallot, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
- How does Caverject work?
- Caverject is a prostaglandin analog. Prostaglandin analogs (used as eye drops for glaucoma) activate FP receptors that relax the eye's drainage tissues, helping fluid flow out more easily. This lowers the pressure inside the eye and protects the optic nerve.
- How is Caverject rated?
- pharmaranks gives Caverject a composite score of 3.0 out of 5, currently based on 1 weighted source (FDA regulatory recall-safety data weighted highest). See our methodology at /how-we-rate.
- Is there a coupon or discount for Caverject?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Caverject. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Caverject?
- Caverject is marketed by Pfizer. You can see Pfizer's full profile, rating, and other products on pharmaranks.
- Is Caverject a brand-name or generic drug?
- Caverject is a brand-name product with the active ingredient Alprostadil.
- Is Caverject available over the counter?
- No. Caverject is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Caverject come in?
- Caverject is currently marketed as injectable, per the FDA's National Drug Code Directory.
- What class of drug is Caverject?
- Caverject is classified as prostaglandin analog, prostaglandin e1 agonist, per the FDA's Established Pharmacologic Class.
- Is Caverject FDA-registered?
- Caverject is on record with the U.S. FDA under application number NDA020755. You can verify this on its official FDA label.
- Has Caverject been recalled by the FDA?
- Caverject has no FDA recalls recorded under its own application in the openFDA enforcement database. Its recall-safety score reflects its manufacturer's overall recall record. This is general reference, not medical advice — check the FDA recall database for the latest alerts.
- Is Caverject safe?
- There's no single safe-or-not verdict. pharmaranks gives Caverject a recall-safety score of 60/100, based on its FDA recall history (no recalls under its own FDA application) — not an efficacy or side-effect rating. Review its FDA-label side effects and warnings before use, and always consult a licensed professional.
Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
What people report to the FDA about ALPROSTADIL
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 1,800 reports naming ALPROSTADIL — the active ingredient in Caverject, and the FDA flagged 91% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- haemoglobin decreased86 reports
- lymphocyte count decreased85 reports
- pyrexia84 reports
- diarrhoea79 reports
- cardiac failure65 reports
- anaemia64 reports
- blood urea increased62 reports
- pneumonia62 reports
Read these as a signal, not a rate. A report does not mean ALPROSTADIL caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label.
Source: openFDA drug/event (FAERS), retrieved September 25, 2026.
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caverject
60/100