Prostaglandin Analog drugs compared

Compare all 12 Prostaglandin Analog drugs side by side, used for conditions such as abortion, incomplete, cystitis, fetal death. They share one FDA-defined mechanism but differ in approved uses, prescription status, brand-vs-generic options, price, and FDA recall-safety record — which our independent rating scores. The highest-rated is carboprost tromethamine.

11 of 12 drugs in this class carry a pharmaranks safety score, ranging 60–72 out of 100 — computed from FDA recall records, not from reviews.

Rated against independent sources·Last updated June 7, 2026·How we rate

Top-rated prostaglandin analog: 1. Carboprost Tromethamine · 2. Cervidil · 3. Durysta

Prostaglandin Analog drugs compared side by side, with pharmaranks' FDA recall-safety rating
Drug	Generic	Form	Status	Used for	Safety ratingFDA recall-based	Pharmacy pays
Carboprost Tromethamine	—	Injectable	Prescription	Abortion, Incomplete, Cystitis	72/100	—
Cervidil	Dinoprostone	Insert	Prescription	Fetal Death, Uterine Neoplasms	72/100	—
Durysta	Bimatoprost	Implant	Prescription	Glaucoma, Open-Angle	72/100	$8
Latisse	Bimatoprost	Drops	Prescription	Glaucoma, Open-Angle	72/100	$8
Lumigan	Bimatoprost	Drops	Prescription	Glaucoma, Open-Angle	72/100	$8
Tafluprost	—	Drops	Prescription	Glaucoma, Open-Angle	72/100	$81
Travatan Z	Travoprost	Drops	Prescription	Glaucoma, Open-Angle	68/100	$9
Caverject Impulse	Alprostadil	Injectable	Prescription	Aortic Arch Syndromes, Aortic Coarctation	60/100	—
Hemabate	Carboprost Tromethamine	Injectable	Prescription	Abortion, Incomplete, Cystitis	60/100	—
Prepidil	Dinoprostone	Topical	Prescription	Fetal Death, Uterine Neoplasms	60/100	—
Prostin Vr Pediatric	Alprostadil	Injectable	Prescription	Aortic Arch Syndromes, Aortic Coarctation	60/100	—
Idose Tr	Travoprost	Implant	Prescription	Glaucoma, Open-Angle	Not yet rated	$9

The safety rating column is unique to pharmaranks — an independent 0–100 score from FDA regulatory recall data. Higher is safer. Not medical advice.

Best prostaglandin analog by condition

for incomplete abortion for cystitis for fetal death for postpartum hemorrhage for uterine neoplasms for gestational trophoblastic disease

Full ranking · 12 drugs

Frequently asked questions

What is the Prostaglandin Analog drug class?

Prostaglandin Analog is an FDA Established Pharmacologic Class (EPC) — a group of drugs that share a mechanism of action. pharmaranks lists 12 Prostaglandin Analog products, each independently rated.

Are all Prostaglandin Analog drugs the same?

No. Prostaglandin Analog drugs share the same core mechanism — that is why they sit in one FDA class — but they differ in their approved uses, available forms, whether they are prescription or over-the-counter, brand-vs-generic options and price, and their FDA recall-safety record.

What conditions do Prostaglandin Analog drugs treat?

Per NIH RxClass drug-classification data, Prostaglandin Analog drugs are used for conditions including abortion, incomplete, cystitis, fetal death, postpartum hemorrhage, uterine neoplasms, gestational trophoblastic disease.

Which Prostaglandin Analog drug is best-rated?

By our independent rating, carboprost tromethamine currently ranks highest among Prostaglandin Analog drugs. Ratings are based on FDA regulatory (recall-safety) data — always consult a professional.

Sources: the Prostaglandin Analog class definition and its member drugs come from the U.S. NLM RxClass (Established Pharmacologic Class); how the class works is summarized from Latanoprost - StatPearls - NCBI Bookshelf. Ratings are pharmaranks’ independent FDA recall-safety analysis.