
bss plus
Bss Plus is a combination medicine containing Calcium Chloride, Dextrose, Glutathione Disulfide, Magnesium Chloride, Potassium Chloride, Sodium Bicarbonate, Sodium Chloride, and Sodium Phosphate.
Calcium Chloride and Dextrose and Glutathione Disulfide and Magnesium Chloride and Potassium Chloride and Sodium Bicarbonate and Sodium Chloride and Sodium Phosphate · by Alcon
Key facts
- Active ingredient
- Calcium Chloride and Dextrose and Glutathione Disulfide and Magnesium Chloride and Potassium Chloride and Sodium Bicarbonate and Sodium Chloride and Sodium Phosphate
- Form
- Kit
- Strength
- Calcium Chloride 0.154MG/ML; Dextrose 0.92MG/ML; Glutathione Disulfide 0.184MG/ML; Magnesium Chloride 0.2MG/ML; Potassium Chloride 0.38MG/ML; Sodium Bicarbonate 2.1MG/ML + 2 more components
- Type
- Prescription (Rx)
- Brand or generic
- Brand-name
- Manufacturer
- Alcon
- What the pharmacy pays
- ~$0.04 per ml — not your price
- FDA application
- NDA018469
What is Bss Plus?
From the FDA label:BSS PLUS ® is a sterile intraocular irrigating solution for use during all intraocular surgical procedures, including those requiring a relatively long intraocular perfusion time (e.g., pars plana vitrectomy, phacoemulsification, extra capsular cataract extraction/lens aspiration, anterior segment reconstruction, etc.). The solution does not contain a preservative and should be prepared just prior to use in surgery. Part I: Part I is a sterile 480 mL solution in a 500 mL single-dose bag to which the Part II concentrate is added. Each mL of Part I contains: sodium chloride 7.44 mg, potassium chloride 0.395 mg, dibasic sodium phosphate 0.433 mg, sodium bicarbonate 2.19 mg, hydrochloric acid and/or sodium hydroxide (to adjust pH), in water for injection. Part II: Part II is a sterile concentrate in a 20 mL single-dose vial for addition to Part I. Each mL of Part II contains: calcium chloride dihydrate 3.85 mg, magnesium chloride hexahydrate 5 mg, dextrose 23 mg, glutathione disulfide (oxidized glutathione) 4.6 mg, in water for injection. After addition of BSS PLUS solution Part II to the Part I bag, each mL of the reconstituted product contains: sodium chloride 7.14 mg, potassium chloride 0.38 mg, calcium chloride dihydrate 0.154 mg, magnesium chloride hexahydrate 0.2 mg, dibasic sodium phosphate 0.42 mg, sodium bicarbonate 2.1 mg, dextrose 0.92 mg, glutathione disulfide…
How to use
The solution should be used according to the standard technique employed by the operating surgeon. Use an administration set with an air-inlet in the plastic spike since the bag does not contain a separate airway tube. Follow the directions for the particular administration set to be used. Insert the spike aseptically into the bag through the center target area of the rubber stopper. Allow the fluid to flow to remove air from the tubing before intraocular irrigation begins.
Side effects
Postoperative inflammatory reactions as well as incidents of corneal edema and corneal decompensation have been reported. Their relationship to the use of BSS PLUS solution has not been established.
Warnings
Important safety information
For IRRIGATION during ophthalmic surgery only. Not for injection or intravenous infusion. Do not use unless product is clear, seal is intact and container is undamaged. Do not use if product is discolored or contains a precipitate.
Who should not take Bss Plus
There are no specific contraindications to the use of BSS PLUS solution; however, contraindications for the surgical procedure during which BSS PLUS solution is to be used should be strictly adhered to.
Dosage forms
Kit
The forms currently marketed in the U.S., per the FDA National Drug Code Directory.
Ways to save
Ask for the generic
Same active ingredient, far cheaper. Is there a generic? →
Request a 90-day supply
Bulk fills usually lower the per-dose price vs monthly refills.
Use copay cards
Manufacturer copay cards & patient-assistance programs — especially for brand drugs.
Compare alternatives
A same-class option may cost less. See alternatives →
Frequently asked questions
- How much does Bss Plus cost?
- Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.04 per ml, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
- Is there a coupon or discount for Bss Plus?
- pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Bss Plus. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
- Who makes Bss Plus?
- Bss Plus is marketed by Alcon. You can see Alcon's full profile, rating, and other products on pharmaranks.
- Is Bss Plus a brand-name or generic drug?
- Bss Plus is a brand-name product with the active ingredient Calcium Chloride and Dextrose and Glutathione Disulfide and Magnesium Chloride and Potassium Chloride and Sodium Bicarbonate and Sodium Chloride and Sodium Phosphate.
- Is Bss Plus available over the counter?
- No. Bss Plus is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
- What forms does Bss Plus come in?
- Bss Plus is currently marketed as kit, per the FDA's National Drug Code Directory.
- Is Bss Plus FDA-registered?
- Bss Plus is on record with the U.S. FDA under application number NDA018469. You can verify this on its official FDA label.
- Is Bss Plus safe?
- There's no single safe-or-not verdict, and we don't yet have a composite recall-safety score for Bss Plus. Review its FDA-label side effects and warnings below, and always consult a licensed professional.
- What are the side effects of Bss Plus?
- Bss Plus's side effects are taken directly from its FDA label. From the label: Postoperative inflammatory reactions as well as incidents of corneal edema and corneal decompensation have been reported. Their relationship to the use of BSS PLUS solution has not been established. Both common and serious reactions are documented in full on this page. This is general reference from the FDA, not medical advice — always consult a professional.
Clinical content sourced from the FDA label via openFDA (U.S. FDA). View the FDA label on DailyMed → Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.
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