BSS PLUS vs RETIN-A

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated October 10, 2026·How we rate

Possible drug interaction. BSS PLUS and RETIN-A are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	BSS PLUS	RETIN-A
Rating	New	74/100
Pharmacy pays	$0.04 /mL	$1.05 /g
Type	RX	RX
Active ingredient	CALCIUM CHLORIDE AND DEXTROSE AND GLUTATHIONE DISULFIDE AND MAGNESIUM CHLORIDE AND POTASSIUM CHLORIDE AND SODIUM BICARBONATE AND SODIUM CHLORIDE AND SODIUM PHOSPHATE	TRETINOIN
Manufacturer	Alcon	Valeant Pharm Intl
Dosage forms	Kit	Topical
Drug class	—	Retinoid
Boxed warning	None	None
Treats	—	Acne Vulgaris, Facial Dermatoses, Acute Promyelocytic Leukemia

bss plus retin-a

Rating

New

74/100

Pharmacy pays

$0.04 /mL

$1.05 /g

Type

Active ingredient

CALCIUM CHLORIDE AND DEXTROSE AND GLUTATHIONE DISULFIDE AND MAGNESIUM CHLORIDE AND POTASSIUM CHLORIDE AND SODIUM BICARBONATE AND SODIUM CHLORIDE AND SODIUM PHOSPHATE

TRETINOIN

Manufacturer

Alcon

Valeant Pharm Intl

Dosage forms

Kit

Topical

Drug class

—

Retinoid

Boxed warning

None

Treats

—

Acne Vulgaris, Facial Dermatoses, Acute Promyelocytic Leukemia

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Frequently asked questions

What is the difference between Bss Plus and Retin-A?

Bss Plus contains Calcium Chloride and Dextrose and Glutathione Disulfide and Magnesium Chloride and Potassium Chloride and Sodium Bicarbonate and Sodium Chloride and Sodium Phosphate, while Retin-A contains Tretinoin — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.