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adrucil

Adrucil (Fluorouracil) is a nucleoside metabolic inhibitor used to treat Breast Neoplasms, Basal Cell Carcinoma, Colonic Neoplasms, Head and Neck Neoplasms.

Fluorouracil · by Pharmacia and Upjohn

Available as a generic: Fluorouracil

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass

Key facts

Active ingredient
Fluorouracil
Form
Injectable
Strength
Fluorouracil 50MG/ML **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons**
Type
Prescription (Rx)
Brand or generic
Brand-name
What the pharmacy pays
~$0.61 per ml — not your price
FDA application
NDA017959
Availability
Discontinued (per FDA)

Drug class

How this class works, per Gemcitabine — LiverTox, NCBI Bookshelf (NIH).

May treat (source: NIH RxClass)

See how Adrucil ranks — best-rated nucleoside metabolic inhibitor for:

Dosage forms

Injectable

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

What does Adrucil treat?
Adrucil (Fluorouracil) may be used to treat breast neoplasms, basal cell carcinoma, colonic neoplasms, head and neck neoplasms, keratosis, pancreatic neoplasms, based on NIH RxClass drug-classification data (conditions a drug may treat — not a verbatim copy of the FDA-approved label). This is general reference, not medical advice.
How does Adrucil work?
Adrucil is a nucleoside metabolic inhibitor. Nucleoside metabolic inhibitors are fake DNA building blocks that fast-dividing cancer cells mistake for the real thing. Once inside, they get incorporated into the cell's DNA and also block enzymes such as ribonucleotide reductase, which together halt DNA copying and cause the cancer cell to die.
How much does Adrucil cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $0.61 per ml, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins.
Is there a coupon or discount for Adrucil?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Adrucil. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Adrucil?
Adrucil is marketed by Pharmacia and Upjohn. You can see Pharmacia and Upjohn's full profile, rating, and other products on pharmaranks.
Is Adrucil a brand-name or generic drug?
Adrucil is a brand-name product with the active ingredient Fluorouracil. Lower-cost generic equivalents containing Fluorouracil are available — ask your pharmacist.
Is Adrucil available over the counter?
No. Adrucil is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Adrucil come in?
Adrucil is currently marketed as injectable, per the FDA's National Drug Code Directory.
What class of drug is Adrucil?
Adrucil is classified as nucleoside metabolic inhibitor, per the FDA's Established Pharmacologic Class.
Is Adrucil FDA-registered?
Adrucil is on record with the U.S. FDA under application number NDA017959. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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