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Grape Seed Extract: uses, dosing, side effects & brands

Grape Seed Extract is a medicine sold in the U.S. under one brand. Below: what the FDA label says, every product that contains it, what the pills look like, and its recall record.

By the pharmaranks editorial teamReviewed against the FDA (openFDA label, NDC Directory & Enforcement) sourcesUpdated Jul 24, 2026How we research

Key facts

Sold as
Grape Seed Extract
Generic available?
Yes

Every grape seed extract product we track (1)

Same active ingredient — different manufacturer, form, price and FDA recall record. That last one is what our independent score measures.

Only one: Grape Seed Extract.

What people report to the FDA about grape seed extract

The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 422 reports naming grape seed extract, and the FDA flagged 60% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:

  • fatigue77 reports
  • dizziness52 reports
  • headache47 reports
  • diarrhoea41 reports
  • cough38 reports
  • nausea38 reports
  • dyspnoea35 reports
  • arthralgia32 reports

Read these as a signal, not a rate. A report does not mean grape seed extract caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label section above.

Source: openFDA drug/event (FAERS), retrieved July 25, 2026.

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Frequently asked questions

What is Grape Seed Extract?

A source of antioxidant proanthocyanidins for circulation and skin.

Can you take grape seed extract with other medicines?

It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run grape seed extract against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.

Is there a generic grape seed extract?

Yes. Our catalog lists 1 generic grape seed extract product alongside the brand versions. A generic has the same active ingredient and must meet the FDA's bioequivalence standard; it usually costs less. Ask your pharmacist which one your plan covers.

Cite this page
APA
pharmaranks. (2026, July 24). Grape Seed Extract: uses, dosing, side effects & brands. https://pharmaranks.com/drugs/grape-seed-extract
MLA
“Grape Seed Extract: uses, dosing, side effects & brands.” pharmaranks, 24 July 2026, https://pharmaranks.com/drugs/grape-seed-extract.

We summarise public FDA and NIH sources — for a clinical claim, cite the primary source we link to as well.

Sources: FDA openFDA drug label, National Drug Code Directory, and Enforcement (recall) database. This page reproduces public FDA data and is not medical advice. Dosing is set by your prescriber.

Read the full FDA label for grape seed extract on DailyMed (NIH) ↗.