Question 1

What is epinephrine?

Accepted Answer

Epinephrine Injection, USP 0.3 mg and 0.15 mg, are single-dose auto-injectors and combination products containing drug and device components. Each Epinephrine Injection, USP 0.3 mg, delivers a single dose of 0.3 mg epinephrine from Epinephrine Injection, USP (0.3 mL) in a sterile solution. Each Epinephrine Injection, USP 0.15 mg, delivers a single dose of 0.15 mg epinephrine from Epinephrine Injection, USP (0.15 mL) in a sterile solution. Epinephrine Injection, USP 0.3 mg and Epinephrine Injection, USP 0.15 mg each contain 1.1 mL of epinephrine solution. 0.3 mL and 0.15 mL epinephrine solution are dispensed for Epinephrine Injection, USP 0.3 mg and Epinephrine Injection, USP 0.15 mg, respectively, when activated. The solution remaining after activation is not available for future use and should be discarded. Each 0.3 mL in Epinephrine Injection, USP 0.3 mg, contains 0.3 mg epinephrine, 2.6 mg sodium chloride, not more than 1.5 mg chlorobutanol, 0.45 mg sodium bisulfite, hydrochloric acid and sodium hydroxide to adjust pH, and water for injection. The pH range is 2.2-5.0. Each 0.15 mL in Epinephrine Injection, USP 0.15 mg, contains 0.15 mg epinephrine, 1.3 mg sodium chloride, not more than 0.75 mg chlorobutanol, 0.225 mg sodium bisulfite, hydrochloric acid and sodium hydroxide to adjust pH, and water for injection. The pH range is 2.2-5.0. Epinephrine is a sympathomimetic…

Question 2

What kind of drug is epinephrine?

Accepted Answer

The FDA classifies epinephrine as a catecholamine. Catecholamines such as epinephrine and norepinephrine are "fight or flight" messengers that switch on adrenergic (alpha and beta) receptors throughout the body, speeding the heart, raising blood pressure by tightening blood vessels, and opening the airways. If you are checking whether it is safe to combine with something else, the class is what matters — two drugs from the same class usually should not be stacked.

Question 3

Can you take epinephrine with other medicines?

Accepted Answer

It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run epinephrine against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.

Question 4

What brand names is epinephrine sold under?

Accepted Answer

We track 13 epinephrine-containing products in the U.S.: Adrenaclick, Sus-Phrine Sulfite Free, Twinject, Symjepi, Epi E Z Pen Jr, Epipen, Epipen E Z Pen and Epipen Jr., and 5 more. They are the same active ingredient; they differ in form, manufacturer, price and FDA recall record.

Question 5

What forms does epinephrine come in?

Accepted Answer

Across the brands we track, epinephrine is currently marketed as injectable, solution, spray/inhaler, metered and spray/inhaler, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.

Question 6

Is there a generic epinephrine?

Accepted Answer

We do not currently list a generic-labelled epinephrine product. That does not always mean none exists — it means none appears under a generic name in the FDA data we track. Ask your pharmacist.

Question 7

Has epinephrine been recalled?

Accepted Answer

The FDA's Enforcement database lists at least 5 recall records whose product description mentions epinephrine. The most recent: Epinephrine Injection (May 14, 2026). A recall applies to specific lots, not to the drug as a whole — check the record for the affected lot numbers.

#	Drug	Rating	Type	Form	Generic?	Typical price
1	Adrenaclick	72/100	Prescription	Injectable	Generic	$3898	View →
2	Sus-Phrine Sulfite Free	72/100	Prescription	Injectable	Generic

Epinephrine: uses, dosing, side effects & brands

Key facts

How epinephrine is dosed

Epinephrine side effects

Every epinephrine product we track (13)

Combination products containing epinephrine

Epinephrine recalls

Frequently asked questions

Who shouldn’t take epinephrine

Epinephrine drug interactions