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duranest

Duranest is a combination medicine containing Epinephrine Bitartrate and Etidocaine Hydrochloride.

Epinephrine Bitartrate and Etidocaine Hydrochloride · by Dentsply Pharm

Not yet rated· sourced from the FDA label
Rated against independent regulatory sources·Last updated June 7, 2026·How we rate
Verified againstopenFDANIH DailyMedRxClass
Lower-cost optionsSave up to 99%
This medication~$3898.29/30
Cheapest in class · abiraterone acetate~$25.50/30
See FDA-approved alternatives

Key facts

Active ingredient
Epinephrine Bitartrate and Etidocaine Hydrochloride
Form
Injectable
Strength
Epinephrine Bitartrate 0.005MG/ML; Etidocaine Hydrochloride 1.5% **Federal Register Determination That Product was not Discontinued or Withdrawn for Safety or Effectiveness reasons**
Type
Prescription (Rx)
Brand or generic
Brand-name
Manufacturer
Dentsply Pharm
What the pharmacy pays
~$3898.29 for 30 — not your price
FDA application
NDA021384
Availability
Discontinued (per FDA)

Dosage forms

Injectable

The forms currently marketed in the U.S., per the FDA National Drug Code Directory.

Ways to save

Ask for the generic

Same active ingredient, far cheaper. Is there a generic? →

Request a 90-day supply

Bulk fills usually lower the per-dose price vs monthly refills.

Use copay cards

Manufacturer copay cards & patient-assistance programs — especially for brand drugs.

Compare alternatives

A same-class option may cost less. See alternatives →

Frequently asked questions

How much does Duranest cost?
Nobody can tell you what you will pay — your price is set by your insurer's formulary, your deductible and the pharmacy's markup, and none of those are published. What IS published is what the pharmacy paid to acquire it: about $3898.29 for 30, per the CMS NADAC survey. Treat that as the floor, not the quote — ask the pharmacist for the cash price as well as your copay, because for cheap generics the cash price often wins. Pharmacies pay less for a same-class option, Abiraterone Acetate — about $25.50 on the same basis.
Is there a coupon or discount for Duranest?
pharmaranks is an independent ratings site, not a pharmacy — we don't issue coupons or sell Duranest. To pay less, ask your prescriber or pharmacist whether a generic equivalent exists, check the manufacturer's copay/savings card and patient-assistance program, and compare a pharmacy discount card against your insurance copay. Prices vary by pharmacy, insurance, and location, so always confirm at the counter. This is general reference, not medical or financial advice.
Who makes Duranest?
Duranest is marketed by Dentsply Pharm. You can see Dentsply Pharm's full profile, rating, and other products on pharmaranks.
Is Duranest a brand-name or generic drug?
Duranest is a brand-name product with the active ingredient Epinephrine Bitartrate and Etidocaine Hydrochloride.
Is Duranest available over the counter?
No. Duranest is a prescription (Rx) medication in the US — you need a prescription from a licensed clinician (in person or via telehealth); it isn't sold over the counter. For some conditions there are OTC alternatives — ask your pharmacist.
What forms does Duranest come in?
Duranest is currently marketed as injectable, per the FDA's National Drug Code Directory.
Is Duranest FDA-registered?
Duranest is on record with the U.S. FDA under application number NDA021384. You can verify this on its official FDA label.

Information is sourced from public FDA regulatory data. Provided for general reference only — not medical advice. Always consult a licensed professional and the current prescribing information.

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