Echothiophate Iodide: uses, dosing, side effects & brands
Echothiophate Iodide is a medicine sold in the U.S. under one brand, for esotropia, glaucoma and open-angle glaucoma. Below: what the FDA label says, every product that contains it, what the pills look like, and its recall record.
Key facts
- Treats
- Esotropia, Glaucoma and Open-Angle Glaucoma
- Available as
- Kit
- Sold as
- Phospholine Iodide
- Prescription?
- Prescription only
- Generic available?
- Not in our catalog
Echothiophate Iodide side effects
Although the relationship, if any, of retinal detachment to the administration of echothiophate iodide for ophthalmic solution has not been established, retinal detachment has been reported in a few cases during the use of echothiophate iodide for ophthalmic solution in adult patients without a previous history of this disorder. Stinging, burning, lacrimation, lid muscle twitching, conjunctival and ciliary redness, browache, induced myopia with visual blurring may occur. Activation of latent iritis or uveitis may occur. Iris cysts may form, and if treatment is continued, may enlarge and obscure vision. This occurrence is more frequent in children. The cysts usually shrink upon discontinuance of the medication or by reducing the frequency of instillation. Rarely, they may rupture or break free into the aqueous. Regular examinations are advisable when the drug is being prescribed for the treatment of accommodative esotropia. Prolonged use may cause conjunctival thickening, obstruction of nasolacrimal canals. Lens opacities have been reported with echothiophate iodide. Paradoxical increase in IOP may follow anticholinesterase instillation. This may be alleviated by prescribing a sympathomimetic mydriatic such as phenylephrine. Cardiac irregularities.
Who shouldn’t take echothiophate iodide
Active uveal inflammation. Most cases of angle-closure glaucoma without iridectomy, due to the possibility of increasing angle block. Hypersensitivity to the active or inactive ingredients.
Echothiophate Iodide drug interactions
Echothiophate iodide for ophthalmic solution potentiates other cholinesterase inhibitors such as succinylcholine or organophosphate and carbamate insecticides. Patients undergoing systemic anticholinesterase treatment should be warned of the possible additive effects of echothiophate iodide for ophthalmic solution.
Every echothiophate iodide product we track (1)
Same active ingredient — different manufacturer, form, price and FDA recall record. That last one is what our independent score measures.
Only one: Phospholine Iodide.
What people report to the FDA about echothiophate iodide
The FDA Adverse Event Reporting System (FAERS) collects reports from patients and clinicians. It holds 8 reports naming echothiophate iodide, and the FDA flagged 50% of those reports as serious. The effects reported most often — leaving out reports about overdose, misuse or the condition being treated, which dominate the raw list for common medicines:
- eye pain2 reports
- headache2 reports
- vision blurred2 reports
- apnoeic attack1 reports
- asthenia1 reports
- bronchospasm1 reports
- chest pain1 reports
- diarrhoea1 reports
Read these as a signal, not a rate. A report does not mean echothiophate iodide caused the effect — anyone can file one, and many describe people taking several medicines for several conditions. Crucially there is no denominator: FAERS does not record how many people took the drug, so these counts cannot be turned into “X% of patients” — a bigger number often just means a more widely used or more talked-about drug. Duplicates exist, and publicity drives reporting. For what is actually established, read the FDA label section above.
Source: openFDA drug/event (FAERS), retrieved July 25, 2026.
Related calculators
Frequently asked questions
What is echothiophate iodide?
Phospholine Iodide (Echothiophate Iodide) is a medication used to treat Esotropia, Glaucoma, Open-Angle Glaucoma, Angle-Closure Glaucoma.
Can you take echothiophate iodide with other medicines?
It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run echothiophate iodide against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.
What forms does echothiophate iodide come in?
Across the brands we track, echothiophate iodide is currently marketed as kit, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.
Is there a generic echothiophate iodide?
We do not currently list a generic-labelled echothiophate iodide product. That does not always mean none exists — it means none appears under a generic name in the FDA data we track. Ask your pharmacist.
Cite this page
- APA
- pharmaranks. (2026, July 24). Echothiophate Iodide: uses, dosing, side effects & brands. https://pharmaranks.com/drugs/echothiophate-iodide
- MLA
- “Echothiophate Iodide: uses, dosing, side effects & brands.” pharmaranks, 24 July 2026, https://pharmaranks.com/drugs/echothiophate-iodide.
We summarise public FDA and NIH sources — for a clinical claim, cite the primary source we link to as well.
Sources: FDA openFDA drug label, National Drug Code Directory, and Enforcement (recall) database. This page reproduces public FDA data and is not medical advice. Dosing is set by your prescriber.
Read the full FDA label for echothiophate iodide on DailyMed (NIH) ↗.