What is acetaminophen?

Acetaminophen is a non-salicylate antipyretic and non-opioid analgesic agent. Its chemical name is N-acetyl-p-aminophenol. Its structural formula is: M.W. 151.16 Acetaminophen Injection, for intravenous use, is a sterile, clear, colorless, non-pyrogenic, isotonic formulation of acetaminophen intended for intravenous infusion. Each 100 mL contains 1,000 mg of Acetaminophen, USP; 3,670 mg of mannitol, 10 mg of cysteine, and hydrochloric acid and sodium hydroxide as pH adjusters, in water for injection. Acetaminophen Injection has a pH between 5.0 and 6.3, and an osmolality of approximately 290 mOsm/kg. Structural Formula

Can you take acetaminophen with other medicines?

It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run acetaminophen against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.

What brand names is acetaminophen sold under?

We track 6 acetaminophen-containing products in the U.S.: Infants' Feverall, Acetaminophen, Acephen, Injectapap, Neopap and Tylenol. They are the same active ingredient; they differ in form, manufacturer, price and FDA recall record.

What forms does acetaminophen come in?

Across the brands we track, acetaminophen is currently marketed as suppository, capsule, injectable, solution, liquid, suspension, syrup, tablet and tablet, extended release, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.

Is there a generic acetaminophen?

Yes. Our catalog lists 1 generic acetaminophen product alongside the brand versions. A generic has the same active ingredient and must meet the FDA's bioequivalence standard; it usually costs less. Ask your pharmacist which one your plan covers.

Has acetaminophen been recalled?

The FDA's Enforcement database lists at least 5 recall records whose product description mentions acetaminophen. The most recent: Oxycodone and Acetaminophen CII Tablets USP (Dec 16, 2025). A recall applies to specific lots, not to the drug as a whole — check the record for the affected lot numbers.

Acetaminophen: uses, dosing, side effects & brands

Acetaminophen is a medicine sold in the U.S. under 6 brand and generic names, for fever and pain. Below: what the FDA label says, every product that contains it, what the pills look like, and its recall record.

By the pharmaranks editorial teamReviewed against the FDA (openFDA label, NDC Directory & Enforcement) sourcesHow we research

Key facts

Treats: Fever and Pain
Available as: Suppository · Capsule · Injectable · Solution · Liquid · Suspension · Syrup · Tablet · Tablet, extended release
Sold as: 6 products — Infants' Feverall, Acetaminophen and Acephen, and others
Prescription?: Both Rx and OTC forms
Generic available?: Yes
Typical price: about $0 for a 30-count supply
Boxed warning: Boxed warning

How acetaminophen is dosed

From the FDA label for Acetaminophen (application NDA204767). Other acetaminophen products — different forms, different strengths — are dosed differently. Follow the label for the one you were prescribed.

Acetaminophen Injection may be given as a single or repeated dose. ( 2.1 ) Acetaminophen Injection should be administered only as a 15-minute intravenous infusion. ( 2.4 ) Adults and Adolescents Weighing 50 kg and Over : 1,000 mg every 6 hours or 650 mg every 4 hours to a maximum of 4,000 mg per day. Minimum dosing interval of 4 hours. ( 2.2 ) Adults and Adolescents Weighing Under 50 kg: 15 mg/kg every 6 hours or 12.5 mg/kg every 4 hours to a maximum of 75 mg/kg per day. Minimum dosing interval of 4 hours. ( 2.2 ) Children: Children 2 to 12 years of age: 15 mg/kg every 6 hours or 12.5 mg/kg every 4 hours to a maximum of 75 mg/kg per day. Minimum dosing interval of 4 hours. ( 2.3 ) 2.1 General Dosing Information Acetaminophen Injection, for intravenous use, may be given as a single or repeated dose for the treatment of acute pain or fever. No dose adjustment is required when converting between oral acetaminophen and acetaminophen injection dosing in adults and adolescents who weigh 50 kg and above. Calculated maximum daily dose of acetaminophen is based on all routes of administration (i.e., intravenous, oral, and rectal) and all products containing acetaminophen. Exceeding the maximum mg/kg daily dose of acetaminophen as described in Tables 1 and 2 may result in hepatic injury, including the risk of liver failure and death. To avoid the risk of overdose, ensure that the total…

Acetaminophen side effects

The following serious adverse reactions are discussed elsewhere in the labeling: Hepatic Injury [see Warnings and Precautions ( 5.1 )] Serious Skin Reactions [see Warnings and Precautions ( 5.2 )] Allergy and Hypersensitivity [see Warnings and Precautions ( 5.4 )] The most common adverse reactions in patients treated with acetaminophen were nausea, vomiting, headache, and insomnia in adult patients; nausea, vomiting, constipation, pruritus, agitation, and atelectasis in pediatric patients. ( 6.1 ) To report SUSPECTED ADVERSE REACTIONS, contact Fresenius Kabi USA, LLC at 1-800-551- 7176 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. 6.1 Clinical Trial Experience Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed cannot be directly compared to rates in other clinical trials and may not reflect the rates observed in practice. Adult Population A total of 1,020 adult patients have received acetaminophen in clinical trials, including 37.3% (n=380) who received 5 or more doses, and 17% (n=173) who received more than 10 doses. Most patients were treated with acetaminophen 1,000 mg every 6 hours. A total of 13.1% (n=134) received acetaminophen 650 mg every 4 hours. All adverse reactions that occurred in adult patients treated with either acetaminophen or placebo in repeated dose, placebo-controlled clinical trials at an incidence ≥…

Every acetaminophen product we track (6)

Same active ingredient — different manufacturer, form, price and FDA recall record. That last one is what our independent score measures.

Acetaminophen products
#	Drug	Rating	Type	Form	Generic?	Typical price
1	Infants' Feverall	70/100	Over-the-counter	Suppository	Generic	$0	View →
2	Acetaminophen Boxed warning

What acetaminophen pills look like

Imprint codes, colour and shape from the FDA’s labelling data. Match the imprint on your pill — or search any imprint.

Acetaminophen pill imprints
Imprint	Strength	Colour	Shape	Maker
AI;II	250 mg / 125 mg	yellow	capsule	—
T;II	250 mg / 125 mg	yellow	oval	—
T;24	50 mg / 325 mg / 40 mg	blue	round	—
A30	50 mg / 325 mg / 40 mg	white	capsule	—
I;I	250 mg / 125 mg	yellow	oval	—
FIORICET;CODEINE

Combination products containing acetaminophen

A combination is a different drug — different dosing, different warnings. It is listed here so you can find it, not so you can substitute it.

Acetaminophen recalls

From the FDA Enforcement database. A recall covers specific lots — not the drug as a whole.

Frequently asked questions

What is acetaminophen?: Acetaminophen is a non-salicylate antipyretic and non-opioid analgesic agent. Its chemical name is N-acetyl-p-aminophenol. Its structural formula is: M.W. 151.16 Acetaminophen Injection, for intravenous use, is a sterile, clear, colorless, non-pyrogenic, isotonic formulation of acetaminophen intended for intravenous infusion. Each 100 mL contains 1,000 mg of Acetaminophen, USP; 3,670 mg of mannitol, 10 mg of cysteine, and hydrochloric acid and sodium hydroxide as pH adjusters, in water for injection. Acetaminophen Injection has a pH between 5.0 and 6.3, and an osmolality of approximately 290 mOsm/kg. Structural Formula
Can you take acetaminophen with other medicines?: It depends on the medicine. We check it against the FDA labels rather than guessing: our interaction checker searches each drug's own label for the other and quotes what it says, naming the section it came from. Run acetaminophen against whatever else you take — and remember that a label not naming a drug is not the same as that combination being safe.
What brand names is acetaminophen sold under?: We track 6 acetaminophen-containing products in the U.S.: Infants' Feverall, Acetaminophen, Acephen, Injectapap, Neopap and Tylenol. They are the same active ingredient; they differ in form, manufacturer, price and FDA recall record.
What forms does acetaminophen come in?: Across the brands we track, acetaminophen is currently marketed as suppository, capsule, injectable, solution, liquid, suspension, syrup, tablet and tablet, extended release, per the FDA's National Drug Code Directory. Each form is dosed differently — follow the label for the exact product you were prescribed.
Is there a generic acetaminophen?: Yes. Our catalog lists 1 generic acetaminophen product alongside the brand versions. A generic has the same active ingredient and must meet the FDA's bioequivalence standard; it usually costs less. Ask your pharmacist which one your plan covers.

Sources: FDA openFDA drug label, National Drug Code Directory, and Enforcement (recall) database. This page reproduces public FDA data and is not medical advice. Dosing is set by your prescriber.