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Best treatments for postpartum hemorrhage

8 products may treat postpartum hemorrhage, spanning FDA drug classes such as ergotamine derivative, prostaglandin analog, ergot derivative. The current highest-rated option is brekiya (autoinjector). Ranked below by our independent recall-safety rating (rated where FDA data exists) — not medical advice; always consult a professional.

Quick answer: Of the 8 drugs we list for postpartum hemorrhage, 6 are available as lower-cost generics, spanning classes such as ergotamine derivative, prostaglandin analog, ergot derivative. They’re ranked by each drug’s FDA recall-safety record — not clinical effectiveness for postpartum hemorrhage — so confirm the right choice with your prescriber.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Top-rated picks for postpartum hemorrhage: 1. Brekiya (Autoinjector) · 2. Carboprost Tromethamine · 3. Hemabate

Top-rated treatments for postpartum hemorrhage, ranked by pharmaranks score
#DrugRatingPharmacy pays
170/100$35View →
270/100View →
364/100View →
4Not yet rated$35View →
5Not yet rated$35View →
6Not yet rated$159View →
7Not yet rated$35View →
8Not yet rated$35View →

Full ranking · 8 treatments

brekiya (autoinjector)

Boxed warning

PrescriptionFDA-sourced

70/100

Brekiya (Autoinjector) (Dihydroergotamine Mesylate) is an ergotamine derivative used to treat Cluster Headache, Postpartum Hemorrhage, Orthostatic Hypotension, Migraine Disorders.

(11 data points)
ergotamine derivativecluster headachepostpartum hemorrhage

Pharmacy pays

From ~$33.73· 2 forms
View details →

carboprost tromethamine

PrescriptionFDA-sourced

70/100

Carboprost Tromethamine is a prostaglandin analog used to treat Incomplete Abortion, Cystitis, Fetal Death, Postpartum Hemorrhage.

(8 data points)
prostaglandin analogabortion, incompletecystitis

Price varies

View details →
PFIZER logo

hemabate

Boxed warning

PrescriptionFDA-sourced

64/100

Hemabate (Carboprost Tromethamine) is a prostaglandin analog used to treat Incomplete Abortion, Cystitis, Fetal Death, Postpartum Hemorrhage.

(61 data points)
prostaglandin analogabortion, incompletecystitis

Price varies

View details →

atzumi

Boxed warning

PrescriptionFDA-sourced

New

Atzumi (Dihydroergotamine Mesylate) is an ergotamine derivative used to treat Cluster Headache, Postpartum Hemorrhage, Orthostatic Hypotension, Migraine Disorders.

ergotamine derivativecluster headachepostpartum hemorrhage

Pharmacy pays

From ~$33.73· 2 forms
View details →

dihydroergotamine mesylate

Boxed warning

PrescriptionFDA-sourced

New

Dihydroergotamine Mesylate is an ergotamine derivative used to treat Cluster Headache, Postpartum Hemorrhage, Orthostatic Hypotension, Migraine Disorders.

ergotamine derivativecluster headachepostpartum hemorrhage

Pharmacy pays

From ~$33.73· 2 forms
View details →

methylergonovine maleate

PrescriptionFDA-sourced

New

Methylergonovine Maleate is an ergot derivative used to treat Postpartum Hemorrhage.

ergot derivativepostpartum hemorrhage

Pharmacy pays

~$158.98 /30

Save up to 73% in class
View details →

Frequently asked

What treats postpartum hemorrhage?
Our catalog lists 8 products that may treat postpartum hemorrhage, based on NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. They're rated where FDA recall-safety data exists; the current top-rated option is brekiya (autoinjector).
What is the best-rated treatment for postpartum hemorrhage?
By our independent recall-safety rating — not an efficacy measure — brekiya (autoinjector) ranks highest among the products we list for postpartum hemorrhage. Always consult a professional.
How are these treatments ranked?
By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.
What types of drugs treat postpartum hemorrhage?
Treatments for postpartum hemorrhage span FDA drug classes including ergotamine derivative, prostaglandin analog, ergot derivative. Compare every option side by side, ranked by independent rating, above.

Treatment associations are derived from NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. This is general reference, not medical advice — always consult a licensed professional.