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Best treatments for postherpetic neuralgia

6 products may treat postherpetic neuralgia, spanning FDA drug classes such as anti-epileptic agent. The current highest-rated option is horizant. Ranked below by our independent recall-safety rating (rated where FDA data exists) — not medical advice; always consult a professional.

Quick answer: Of the 6 drugs we list for postherpetic neuralgia, 5 are available as lower-cost generics, spanning classes such as anti-epileptic agent. They’re ranked by each drug’s FDA recall-safety record — not clinical effectiveness for postherpetic neuralgia — so confirm the right choice with your prescriber.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate
Treatments we list for postherpetic neuralgia
#DrugRatingPharmacy pays
170/100View →
2Not yet rated$1View →
3Not yet rated$1View →
4Not yet rated$2View →
5Not yet rated$2View →
6Not yet rated$1View →

Full ranking · 6 treatments

horizant

PrescriptionFDA-sourced

70/100

Horizant (Gabapentin Enacarbil) is a medication used to treat Bipolar Disorder, Partial Epilepsies, Phobic Disorders, Postherpetic Neuralgia.

(3 data points)
bipolar disorderepilepsies, partialphobic disorders

Price varies

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gabapentin

PrescriptionFDA-sourced

New

Gabapentin is an anti-epileptic agent used to treat Bipolar Disorder, Partial Epilepsies, Phobic Disorders, Postherpetic Neuralgia.

anti-epileptic agentbipolar disorderepilepsies, partial

Pharmacy pays

From ~$0.63/30· 8 forms Save up to 16% in class
View details →
ALMATICA logo

gralise

PrescriptionFDA-sourced

New

Gralise (Gabapentin) is an anti-epileptic agent used to treat Bipolar Disorder, Partial Epilepsies, Phobic Disorders, Postherpetic Neuralgia.

anti-epileptic agentbipolar disorderepilepsies, partial

Pharmacy pays

From ~$0.63/30· 8 forms Save up to 16% in class
View details →
UPJOHN logo

lyrica

PrescriptionFDA-sourced

New

Lyrica (Pregabalin) is a medication used to treat Fibromyalgia, Seizures, Spinal Cord Injuries, Postherpetic Neuralgia.

fibromyalgiaseizuresspinal cord injuries

Pharmacy pays

From ~$1.33/30· 8 forms
View details →
UPJOHN logo

lyrica cr

PrescriptionFDA-sourced

New

Lyrica CR (Pregabalin) is a medication used to treat Fibromyalgia, Seizures, Spinal Cord Injuries, Postherpetic Neuralgia.

fibromyalgiaseizuresspinal cord injuries

Pharmacy pays

From ~$1.33/30· 8 forms
View details →

neurontin

PrescriptionFDA-sourced

New

Neurontin (Gabapentin) is an anti-epileptic agent used to treat Bipolar Disorder, Partial Epilepsies, Phobic Disorders, Postherpetic Neuralgia.

anti-epileptic agentbipolar disorderepilepsies, partial

Pharmacy pays

From ~$0.63/30· 8 forms Save up to 16% in class
View details →

Frequently asked

What treats postherpetic neuralgia?
Our catalog lists 6 products that may treat postherpetic neuralgia, based on NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. They're rated where FDA recall-safety data exists; the current top-rated option is horizant.
What is the best-rated treatment for postherpetic neuralgia?
By our independent recall-safety rating — not an efficacy measure — horizant ranks highest among the products we list for postherpetic neuralgia. Always consult a professional.
How are these treatments ranked?
By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.
What types of drugs treat postherpetic neuralgia?
Treatments for postherpetic neuralgia span FDA drug classes including anti-epileptic agent. Compare every option side by side, ranked by independent rating, above.

Treatment associations are derived from NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. This is general reference, not medical advice — always consult a licensed professional.