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Best treatments for graft vs host disease

10 products may treat graft vs host disease, spanning FDA drug classes such as calcineurin inhibitor immunosuppressant, antimetabolite immunosuppressant, anthrax protective antigen-directed antibody. The current highest-rated option is prograf. Ranked below by our independent recall-safety rating (rated where FDA data exists) — not medical advice; always consult a professional.

Quick answer: Of the 10 drugs we list for graft vs host disease, 6 are available as lower-cost generics, spanning classes such as calcineurin inhibitor immunosuppressant, antimetabolite immunosuppressant, anthrax protective antigen-directed antibody. They’re ranked by each drug’s FDA recall-safety record — not clinical effectiveness for graft vs host disease — so confirm the right choice with your prescriber.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Top-rated picks for graft vs host disease: 1. Prograf · 2. Astagraf XL · 3. Myfortic

Top-rated treatments for graft vs host disease, ranked by pharmaranks score
#DrugRatingPharmacy pays
172/100$1View →
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Full ranking · 10 treatments

#1 of 10 in Calcineurin Inhibitor Immunosuppressant

prograf

Boxed warning

PrescriptionFDA-sourced

72/100

Prograf (Tacrolimus) is a calcineurin inhibitor immunosuppressant used to treat Atopic Dermatitis, Graft Vs Host Disease.

(4 data points)
calcineurin inhibitor immunosuppressantdermatitis, atopicgraft vs host disease

Pharmacy pays

From ~$0.15· 5 forms
View details →

astagraf xl

Boxed warning

PrescriptionFDA-sourced

70/100

Astagraf XL (Tacrolimus) is a calcineurin inhibitor immunosuppressant used to treat Atopic Dermatitis, Graft Vs Host Disease.

(4 data points)
calcineurin inhibitor immunosuppressantdermatitis, atopicgraft vs host disease

Pharmacy pays

From ~$0.15· 5 forms
View details →
NOVARTIS logo

myfortic

Boxed warning

PrescriptionFDA-sourced

70/100

Myfortic (Mycophenolate Sodium) is an antimetabolite immunosuppressant used to treat Graft Vs Host Disease.

(13 data points)
antimetabolite immunosuppressantgraft vs host disease

Pharmacy pays

From ~$0.14· 3 forms
View details →

anthim

Boxed warning

PrescriptionFDA-sourced

New

Anthim (Obiltoxaximab) is an anthrax protective antigen-directed antibody used to treat Anthrax, Crohn Disease, Graft Vs Host Disease.

anthrax protective antigen-directed antibodyanthraxcrohn disease

Price varies

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cellcept

Boxed warning

PrescriptionFDA-sourced

New

Cellcept (Mycophenolate Mofetil) is an antimetabolite immunosuppressant used to treat Graft Vs Host Disease, Psoriasis.

antimetabolite immunosuppressantgraft vs host diseasepsoriasis

Price varies

View details →

envarsus xr

Boxed warning

PrescriptionFDA-sourced

New

Envarsus XR (Tacrolimus) is a calcineurin inhibitor immunosuppressant used to treat Atopic Dermatitis, Graft Vs Host Disease.

calcineurin inhibitor immunosuppressantdermatitis, atopicgraft vs host disease

Pharmacy pays

From ~$0.15· 5 forms
View details →

Frequently asked

What treats graft vs host disease?
Our catalog lists 10 products that may treat graft vs host disease, based on NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. They're rated where FDA recall-safety data exists; the current top-rated option is prograf.
What is the best-rated treatment for graft vs host disease?
By our independent recall-safety rating — not an efficacy measure — prograf ranks highest among the products we list for graft vs host disease. Always consult a professional.
How are these treatments ranked?
By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.
What types of drugs treat graft vs host disease?
Treatments for graft vs host disease span FDA drug classes including calcineurin inhibitor immunosuppressant, antimetabolite immunosuppressant, anthrax protective antigen-directed antibody. Compare every option side by side, ranked by independent rating, above.

Treatment associations are derived from NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. This is general reference, not medical advice — always consult a licensed professional.