Calcineurin Inhibitor Immunosuppressant drugs compared
Compare all 15 Calcineurin Inhibitor Immunosuppressant drugs side by side, used for conditions such as arthritis, rheumatoid, glomerulosclerosis, focal segmental, lupus erythematosus, systemic. They share one FDA-defined mechanism but differ in approved uses, prescription status, brand-vs-generic options, price, and FDA recall-safety record — which our independent rating scores. The highest-rated is gengraf.
Top-rated calcineurin inhibitor immunosuppressant: 1. Gengraf · 2. Prograf · 3. Restasis Multidose
| Drug | Generic | Form | Status | Used for | Safety ratingFDA recall-based | Pharmacy pays |
|---|---|---|---|---|---|---|
| Gengraf | Cyclosporine | Capsule | Prescription | Arthritis, Rheumatoid, Glomerulosclerosis, Focal Segmental | 72/100 | $53 |
| Prograf | Tacrolimus | Capsule | Prescription | Dermatitis, Atopic, Graft Vs Host Disease | 72/100 | $1 |
| Restasis Multidose | Cyclosporine | Emulsion | Prescription | Arthritis, Rheumatoid, Glomerulosclerosis, Focal Segmental | 72/100 | $53 |
| Astagraf XL | Tacrolimus | Capsule | Prescription | Dermatitis, Atopic, Graft Vs Host Disease | 70/100 | $1 |
| Neoral | Cyclosporine | Capsule | Prescription | Arthritis, Rheumatoid, Glomerulosclerosis, Focal Segmental | 70/100 | $53 |
| Sandimmune | Cyclosporine | Capsule | Prescription | Arthritis, Rheumatoid, Glomerulosclerosis, Focal Segmental | 70/100 | $53 |
| Verkazia | Cyclosporine | Emulsion | Prescription | Arthritis, Rheumatoid, Glomerulosclerosis, Focal Segmental | 70/100 | $53 |
| Vevye | Cyclosporine | Drops | Prescription | Arthritis, Rheumatoid, Glomerulosclerosis, Focal Segmental | 70/100 | $53 |
| Cyclosporine | — | Capsule | Prescription | Arthritis, Rheumatoid, Glomerulosclerosis, Focal Segmental | 66/100 | $53 |
| Cequa | Cyclosporine | Drops | Prescription | Arthritis, Rheumatoid, Glomerulosclerosis, Focal Segmental | Not yet rated | $53 |
| Elidel | Pimecrolimus | Topical | Prescription | Dermatitis, Atopic | Not yet rated | $3 |
| Envarsus XR | Tacrolimus | Tablet | Prescription | Dermatitis, Atopic, Graft Vs Host Disease | Not yet rated | $1 |
The safety rating column is unique to pharmaranks — an independent 0–100 score from FDA regulatory recall data. Higher is safer. Not medical advice.
Best calcineurin inhibitor immunosuppressant by condition
Full ranking · 15 drugs
- 172/100
gengraf
Cyclosporine
- 272/100
prograf
Tacrolimus
- 372/100
restasis multidose
Cyclosporine
- 470/100
astagraf xl
Tacrolimus
- 570/100
neoral
Cyclosporine
- 670/100
sandimmune
Cyclosporine
- 770/100
verkazia
Cyclosporine
- 870/100
vevye
Cyclosporine
- 966/100
cyclosporine
Cyclosporine
- 10New
cequa
Cyclosporine
- 11New
elidel
Pimecrolimus
- 12New
envarsus xr
Tacrolimus
- 13New
lupkynis
Voclosporin
- 14New
protopic
Tacrolimus
- 15New
tacrolimus
Tacrolimus
Frequently asked questions
What is the Calcineurin Inhibitor Immunosuppressant drug class?
Calcineurin Inhibitor Immunosuppressant is an FDA Established Pharmacologic Class (EPC) — a group of drugs that share a mechanism of action. pharmaranks lists 15 Calcineurin Inhibitor Immunosuppressant products, each independently rated.
Are all Calcineurin Inhibitor Immunosuppressant drugs the same?
No. Calcineurin Inhibitor Immunosuppressant drugs share the same core mechanism — that is why they sit in one FDA class — but they differ in their approved uses, available forms, whether they are prescription or over-the-counter, brand-vs-generic options and price, and their FDA recall-safety record.
What conditions do Calcineurin Inhibitor Immunosuppressant drugs treat?
Per NIH RxClass drug-classification data, Calcineurin Inhibitor Immunosuppressant drugs are used for conditions including arthritis, rheumatoid, glomerulosclerosis, focal segmental, lupus erythematosus, systemic, myasthenia gravis, psoriasis, dermatitis, atopic.
Which Calcineurin Inhibitor Immunosuppressant drug is best-rated?
By our independent rating, gengraf currently ranks highest among Calcineurin Inhibitor Immunosuppressant drugs. Ratings are based on FDA regulatory (recall-safety) data — always consult a professional.
Sources: the Calcineurin Inhibitor Immunosuppressant class definition and its member drugs come from the U.S. NLM RxClass (Established Pharmacologic Class); how the class works is summarized from Calcineurin Inhibitors - StatPearls - NCBI Bookshelf. Ratings are pharmaranks’ independent FDA recall-safety analysis.