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Best treatments for bacterial conjunctivitis

9 products may treat bacterial conjunctivitis, spanning FDA drug classes such as quinolone antimicrobial, fluoroquinolone antibacterial, corticosteroid. The current highest-rated option is ocuflox. Ranked below by our independent recall-safety rating (rated where FDA data exists) — not medical advice; always consult a professional.

Quick answer: Of the 9 drugs we list for bacterial conjunctivitis, all are available as lower-cost generics, spanning classes such as quinolone antimicrobial, fluoroquinolone antibacterial, corticosteroid. They’re ranked by each drug’s FDA recall-safety record — not clinical effectiveness for bacterial conjunctivitis — so confirm the right choice with your prescriber.

Rated against independent regulatory sources·Last updated August 19, 2026·How we rate

Understanding bacterial conjunctivitis

Bacterial conjunctivitis, commonly called pink eye, is inflammation of the conjunctiva, the clear tissue that lines the inside of the eyelids and covers the white of the eye. The CDC notes it is very contagious and caused by many types of bacteria, including staph and strep; in children it is often caused by Haemophilus influenzae, Streptococcus pneumoniae, or Moraxella catarrhalis. According to the American Academy of Ophthalmology, it tends to cause a thicker, yellow-green discharge, and eyelid crusting overnight is most often caused by bacteria (MedlinePlus). The AAO notes that eye pain is usually associated with the bacterial form, though some people have little or no discharge. A healthcare provider usually diagnoses it by asking about symptoms and examining the eye; a swab of the conjunctiva may be taken for analysis in some cases (MedlinePlus). The CDC states acute bacterial conjunctivitis is typically self-limited within 1 to 2 weeks, though topical antibiotic therapy may reduce the duration of disease. Management centers on hygiene and, when appropriate, antibiotic eye drops. This is general information, not medical advice; see a clinician for diagnosis and care.

First-line treatment

The American Academy of Ophthalmology's Conjunctivitis Preferred Practice Pattern states that mild bacterial conjunctivitis is likely to be self-limited and cautions that "indiscriminate use of topical antibiotics or corticosteroids should be avoided." When a topical antibiotic is used, the AAO notes that "no evidence exists demonstrating the superiority of any topical antibiotic agent." The CDC adds that acute bacterial conjunctivitis is typically self-limited within 1 to 2 weeks, but topical antibiotic therapy may reduce the duration of disease. Hyperacute or suspected gonococcal conjunctivitis is a vision-threatening condition: the AAO states it requires immediate systemic therapy, and the CDC notes it requires both parenteral and topical antibiotics. Alongside any prescribed drops, MedlinePlus emphasizes hygiene such as frequent handwashing and not sharing towels. A clinician individualizes treatment based on severity and risk factors.

Top-rated picks for bacterial conjunctivitis: 1. Ocuflox · 2. Zymaxid · 3. Ciloxan

Top-rated treatments for bacterial conjunctivitis, ranked by pharmaranks score
#DrugRatingPharmacy pays
172/100$1View →
272/100$9View →
368/100$4View →
4Not yet rated$20View →
5Not yet rated$4View →
6Not yet rated$20View →
7Not yet rated$20View →
8Not yet rated$20View →
9Not yet rated$20View →

Full ranking · 9 treatments

#1 of 4 in Quinolone Antimicrobial

ocuflox

PrescriptionFDA-sourced

72/100

Ocuflox (Ofloxacin) is a quinolone antimicrobial used to treat Bronchitis, Chlamydia Infections, Bacterial Conjunctivitis, Corneal Ulcer.

(4 data points)
quinolone antimicrobialbronchitischlamydia infections

Pharmacy pays

From ~$1.12· 2 forms
View details →
ABBVIE logo
#1 of 4 in Quinolone Antimicrobial

zymaxid

PrescriptionFDA-sourced

72/100

Zymaxid (Gatifloxacin) is a quinolone antimicrobial used to treat Bronchitis, Bacterial Conjunctivitis, Cystitis, Escherichia Coli Infections.

(6 data points)
quinolone antimicrobialbronchitisconjunctivitis, bacterial

Pharmacy pays

$8.98 /mL

Save up to 87% in class
View details →
SANDOZ logo
#2 of 3 in Fluoroquinolone Antibacterial

ciloxan

PrescriptionFDA-sourced

68/100

Ciloxan (Ciprofloxacin Hydrochloride) is a fluoroquinolone antibacterial used to treat Anthrax, Infectious Arthritis, Bacteroides Infections, Campylobacter Infections.

(23 data points)
fluoroquinolone antibacterialquinolone antimicrobialanthrax

Pharmacy pays

From ~$2.64/30· 5 forms
View details →

alrex

PrescriptionFDA-sourced

New

Alrex (Loteprednol Etabonate) is a corticosteroid used to treat Allergic Conjunctivitis, Bacterial Conjunctivitis, Viral Conjunctivitis, Edema.

corticosteroidconjunctivitis, allergicconjunctivitis, bacterial

Pharmacy pays

From ~$18.21· 2 forms Save up to 99% in class
View details →

cetraxal

PrescriptionFDA-sourced

New

Cetraxal (Ciprofloxacin Hydrochloride) is a fluoroquinolone antibacterial used to treat Anthrax, Infectious Arthritis, Bacteroides Infections, Campylobacter Infections.

fluoroquinolone antibacterialquinolone antimicrobialanthrax

Pharmacy pays

From ~$2.64/30· 5 forms
View details →
ALCON logo

eysuvis

PrescriptionFDA-sourced

New

Eysuvis (Loteprednol Etabonate) is a corticosteroid used to treat Allergic Conjunctivitis, Bacterial Conjunctivitis, Viral Conjunctivitis, Edema.

corticosteroidconjunctivitis, allergicconjunctivitis, bacterial

Pharmacy pays

From ~$18.21· 2 forms Save up to 99% in class
View details →

Frequently asked

What treats bacterial conjunctivitis?
Our catalog lists 9 products that may treat bacterial conjunctivitis, based on NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. They're rated where FDA recall-safety data exists; the current top-rated option is ocuflox.
What is the best-rated treatment for bacterial conjunctivitis?
By our independent recall-safety rating — not an efficacy measure — ocuflox ranks highest among the products we list for bacterial conjunctivitis. Always consult a professional.
How are these treatments ranked?
By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.
What types of drugs treat bacterial conjunctivitis?
Treatments for bacterial conjunctivitis span FDA drug classes including quinolone antimicrobial, fluoroquinolone antibacterial, corticosteroid. Compare every option side by side, ranked by independent rating, above.

Treatment associations are derived from NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. This is general reference, not medical advice — always consult a licensed professional.

Sources

The clinical overview above is written from these authoritative public-health and medical-society sources, independently reviewed against each.