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Best treatments for amenorrhea

8 products may treat amenorrhea, spanning FDA drug classes such as progesterone, progestin, ergot derivative. The current highest-rated option is crinone. Ranked below by our independent recall-safety rating (rated where FDA data exists) — not medical advice; always consult a professional.

Quick answer: Of the 8 drugs we list for amenorrhea, all are available as lower-cost generics, spanning classes such as progesterone, progestin, ergot derivative. They’re ranked by each drug’s FDA recall-safety record — not clinical effectiveness for amenorrhea — so confirm the right choice with your prescriber.

Rated against independent regulatory sources·Last updated August 22, 2026·How we rate

Top-rated picks for amenorrhea: 1. Crinone · 2. Depo-Provera · 3. Depo-Subq Provera 104

Top-rated treatments for amenorrhea, ranked by pharmaranks score
#DrugRatingPharmacy pays
170/100$12View →
264/100$563View →
364/100$563View →
464/100$563View →
560/100$52View →
6Not yet rated$52View →
7Not yet rated$52View →
8Not yet rated$12View →

Full ranking · 8 treatments

crinone

PrescriptionFDA-sourced

70/100

Crinone (Progesterone) is a progesterone used to treat Amenorrhea, Endometrial Hyperplasia, Female Infertility, Uterine Hemorrhage.

(9 data points)
progesteroneamenorrheaendometrial hyperplasia

Pharmacy pays

From ~$6.46/30· 4 forms
View details →
PFIZER logo

depo-provera

Boxed warning

PrescriptionFDA-sourced

64/100

Depo-Provera (Medroxyprogesterone Acetate) is a progestin used to treat Amenorrhea, Breast Neoplasms, Renal Cell Carcinoma, Endometrial Hyperplasia.

(61 data points)
progestinamenorrheabreast neoplasms

Pharmacy pays

From ~$3.49/30· 4 forms Save up to 99% in class
View details →
PFIZER logo

depo-subq provera 104

Boxed warning

PrescriptionFDA-sourced

64/100

Depo-Subq Provera 104 (Medroxyprogesterone Acetate) is a progestin used to treat Amenorrhea, Breast Neoplasms, Renal Cell Carcinoma, Endometrial Hyperplasia.

(61 data points)
progestinamenorrheabreast neoplasms

Pharmacy pays

From ~$3.49/30· 4 forms Save up to 99% in class
View details →
PFIZER logo

provera

Boxed warning

PrescriptionFDA-sourced

64/100

Provera (Medroxyprogesterone Acetate) is a progestin used to treat Amenorrhea, Breast Neoplasms, Renal Cell Carcinoma, Endometrial Hyperplasia.

(61 data points)
progestinamenorrheabreast neoplasms

Pharmacy pays

From ~$3.49/30· 4 forms Save up to 99% in class
View details →
#3 of 3 in Ergot Derivative

bromocriptine mesylate

PrescriptionFDA-sourced

60/100

Bromocriptine Mesylate is an ergot derivative used to treat Acromegaly, Adenoma, Amenorrhea, Galactorrhea.

(44 data points)
ergot derivativeacromegalyadenoma

Pharmacy pays

From ~$50.78/30· 2 forms Save up to 18% in class
View details →

cycloset

PrescriptionFDA-sourced

New

Cycloset (Bromocriptine Mesylate) is an ergot derivative used to treat Acromegaly, Adenoma, Amenorrhea, Galactorrhea.

ergot derivativeacromegalyadenoma

Pharmacy pays

From ~$50.78/30· 2 forms Save up to 18% in class
View details →

Frequently asked

What treats amenorrhea?
Our catalog lists 8 products that may treat amenorrhea, based on NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. They're rated where FDA recall-safety data exists; the current top-rated option is crinone.
What is the best-rated treatment for amenorrhea?
By our independent recall-safety rating — not an efficacy measure — crinone ranks highest among the products we list for amenorrhea. Always consult a professional.
How are these treatments ranked?
By our independent score, currently based on FDA regulatory recall-safety data (the methodology blends additional sources as they come online). See the How we rate page.
What types of drugs treat amenorrhea?
Treatments for amenorrhea span FDA drug classes including progesterone, progestin, ergot derivative. Compare every option side by side, ranked by independent rating, above.

Treatment associations are derived from NIH RxClass (MED-RT “may treat”) drug-classification data — not the verbatim FDA label. This is general reference, not medical advice — always consult a licensed professional.