ZANTAC 25 vs ZANTAC 300

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Attribute	ZANTAC 25	ZANTAC 300
Rating	New	70/100
Pharmacy pays	—	—
Type	RX	RX
Active ingredient	RANITIDINE HYDROCHLORIDE	RANITIDINE HYDROCHLORIDE
Manufacturer	Glaxo Grp Ltd	Glaxosmithkline
Dosage forms	Tablet, effervescent	Capsule, Tablet
Drug class	—	—
Boxed warning	None	None
Half-life	about 2.5 to 3 hours	about 2.5 to 3 hours
Treats	Duodenal Ulcer, Peptic Esophagitis, Gastroesophageal Reflux	Duodenal Ulcer, Peptic Esophagitis, Gastroesophageal Reflux

zantac 25 zantac 300

Rating

New

70/100

Pharmacy pays

—

Type

Active ingredient

RANITIDINE HYDROCHLORIDE

Manufacturer

Glaxo Grp Ltd

Glaxosmithkline

Dosage forms

Tablet, effervescent

Capsule, Tablet

Drug class

—

Boxed warning

None

Half-life

about 2.5 to 3 hours

Treats

Duodenal Ulcer, Peptic Esophagitis, Gastroesophageal Reflux

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Frequently asked questions

What is the difference between Zantac 25 and Zantac 300?

Both Zantac 25 and Zantac 300 share the active ingredient Ranitidine Hydrochloride.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.