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ZANTAC 150 vs ZANTAC 300

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 16, 2026·How we rate

Rating

70/100
70/100

Pharmacy pays

Type

RX
RX

Active ingredient

RANITIDINE HYDROCHLORIDE
RANITIDINE HYDROCHLORIDE

Dosage forms

Tablet
Capsule, Tablet

Drug class

Boxed warning

None
None

Half-life

about 2.5 to 3 hours
about 2.5 to 3 hours

Treats

Duodenal Ulcer, Peptic Esophagitis, Gastroesophageal Reflux
Duodenal Ulcer, Peptic Esophagitis, Gastroesophageal Reflux

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Frequently asked questions

Which is better-rated, Zantac 150 or Zantac 300?

Zantac 150 and Zantac 300 are tied at 3.5 out of 5 by our independent rating.

What is the difference between Zantac 150 and Zantac 300?

Both Zantac 150 and Zantac 300 share the active ingredient Ranitidine Hydrochloride.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.