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LIDOCAINE HYDROCHLORIDE PRESERVATIVE FREE vs XYLOCAINE DENTAL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 23, 2026·How we rate

Rating

72/100
New

Pharmacy pays

$0.24 /mL
$0.24 /mL

Type

RX
RX

Active ingredient

LIDOCAINE HYDROCHLORIDE
LIDOCAINE HYDROCHLORIDE

Dosage forms

Injectable
Injectable

Drug class

Amide Local Anesthetic
Amide Local Anesthetic

Boxed warning

None
None

Treats

Burns, Esophageal Diseases, Mouth Diseases
Burns, Esophageal Diseases, Mouth Diseases

Frequently asked questions

Which is cheaper, Lidocaine Hydrochloride Preservative Free or Xylocaine Dental?

Pharmacies pay about the same to acquire either one — roughly $0.24 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Lidocaine Hydrochloride Preservative Free and Xylocaine Dental?

Both Lidocaine Hydrochloride Preservative Free and Xylocaine Dental share the active ingredient Lidocaine Hydrochloride.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.