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ROXICET 5/500 vs XARTEMIS XR

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 18, 2026·How we rate

Rating

New
70/100

Pharmacy pays

$0.03 /mL
$0.03 /mL

Type

RX
RX

Active ingredient

ACETAMINOPHEN AND OXYCODONE HYDROCHLORIDE
ACETAMINOPHEN AND OXYCODONE HYDROCHLORIDE

Manufacturer

Dosage forms

Tablet
Tablet, extended release

Drug class

Boxed warning

None
None

Half-life

about 3.5 to 4 hours
about 3.5 to 4 hours

Frequently asked questions

Which is cheaper, Roxicet 5/500 or Xartemis XR?

Pharmacies pay about the same to acquire either one — roughly $0.03 per ml, per the CMS NADAC survey. That is not what you will be charged: your price is set by your insurer and the pharmacy, not by what the drug cost them.

What is the difference between Roxicet 5/500 and Xartemis XR?

Both Roxicet 5/500 and Xartemis XR share the active ingredient Acetaminophen and Oxycodone Hydrochloride.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.