SURMONTIL vs TOFRANIL

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. SURMONTIL and TOFRANIL are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Attribute	SURMONTIL	TOFRANIL
Rating	New	70/100
Pharmacy pays	—	~$2.54 /30
Type	RX	RX
Active ingredient	TRIMIPRAMINE MALEATE	IMIPRAMINE HYDROCHLORIDE
Manufacturer	Teva Womens	Novartis
Dosage forms	Capsule	Tablet, Injectable
Drug class	Tricyclic Antidepressant	Tricyclic Antidepressant
Boxed warning	None	None
Treats	Depressive Disorder	Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Enuresis

surmontil tofranil

Rating

New

70/100

Pharmacy pays

—

~$2.54 /30

Type

Active ingredient

TRIMIPRAMINE MALEATE

IMIPRAMINE HYDROCHLORIDE

Manufacturer

Teva Womens

Novartis

Dosage forms

Capsule

Tablet, Injectable

Drug class

Tricyclic Antidepressant

Boxed warning

None

Treats

Depressive Disorder

Attention Deficit Disorder with Hyperactivity, Depressive Disorder, Enuresis

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Frequently asked questions

What is the difference between Surmontil and Tofranil?

Surmontil contains Trimipramine Maleate, while Tofranil contains Imipramine Hydrochloride — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.