Skip to content
ppharmaranks
Menu

SPRYCEL vs ZORTRESS

Independent side-by-side comparison.

Rated against independent regulatory sources·Last updated August 21, 2026·How we rate

Possible drug interaction. SPRYCEL and ZORTRESS are different prescription medicines. Combining or switching between them can cause interactions — talk to a pharmacist or prescriber before making changes. This page is not medical advice.

Rating

72/100
70/100

Pharmacy pays

~$839.19 /30
~$229.16 /30

Type

RX
RX

Active ingredient

DASATINIB
EVEROLIMUS

Dosage forms

Tablet
Tablet

Drug class

Kinase Inhibitor
Kinase Inhibitor

Boxed warning

Half-life

about 30 hours (mean terminal elimination half-life)

Treats

Lymphoid Leukemia, Myeloid Leukemia

Frequently asked questions

Which is better-rated, Sprycel or Zortress?

By our independent rating, Sprycel scores higher — 3.6 vs 3.5 out of 5 for Zortress. Ratings are based on FDA regulatory (recall-safety) data.

Which is cheaper, Sprycel or Zortress?

Zortress costs pharmacies less to acquire — about $229.16 vs $839.19 for a 30-count supply, per the CMS NADAC survey. That gap is in the pharmacy's cost of goods, not necessarily in what you pay: your price is set afterwards by your insurer and the pharmacy.

What is the difference between Sprycel and Zortress?

Sprycel contains Dasatinib, while Zortress contains Everolimus — they have different active ingredients.

Ratings are based on FDA regulatory (recall-safety) data. This comparison is for general reference only — not medical advice. Always consult a licensed professional before choosing or switching a medication.